Staging of the Baboon Response to Group A Streptococci Administered Intramuscularly: A Descriptive Study of the Clinical Symptoms and Clinical Chemical Response Patterns

Taylor Jr., Fletcher B.; Bryant, Amy E.; Blick, Kenneth E.; Hack, Eric; Jansen, Patty M.; Kosanke, Stanley D.; Stevens, Dennis L.
July 1999
Clinical Infectious Diseases;7/1/99, Vol. 29 Issue 1, p167
Academic Journal
Focuses on a study which correlated the systemic inflammatory and hemostatic events with three stages of development of soft-tissue lesions in Group A streptococcal infections. How close the primate model mimics streptococcal toxic shock syndrome (TSS) seen in humans; Comparison of the systemic and local tissue responses at the site of injection of GAS; Clinical staging of the responses of survivors to intramuscular injection of GAS.


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