Estimating and comparing incidence and prevalence of chronic diseases by combining GP registry data: the role of uncertainty

van Baal, Pieter H.; Engelfriet, Peter M.; Hoogenveen, Rudolf T.; Poos, Marinus J.; van den Dungen, Catharina; Boshuizen, Hendriek C.
January 2011
BMC Public Health;2011, Vol. 11 Issue 1, p163
Academic Journal
Background: Estimates of disease incidence and prevalence are core indicators of public health. The manner in which these indicators stand out against each other provide guidance as to which diseases are most common and what health problems deserve priority. Our aim was to investigate how routinely collected data from different general practitioner registration networks (GPRNs) can be combined to estimate incidence and prevalence of chronic diseases and to explore the role of uncertainty when comparing diseases. Methods: Incidence and prevalence counts, specified by gender and age, of 18 chronic diseases from 5 GPRNs in the Netherlands from the year 2007 were used as input. Generalized linear mixed models were fitted with the GPRN identifier acting as random intercept, and age and gender as explanatory variables. Using predictions of the regression models we estimated the incidence and prevalence for 18 chronic diseases and calculated a stochastic ranking of diseases in terms of incidence and prevalence per 1,000. Results: Incidence was highest for coronary heart disease and prevalence was highest for diabetes if we looked at the point estimates. The between GPRN variance in general was higher for incidence than for prevalence. Since uncertainty intervals were wide for some diseases and overlapped, the ranking of diseases was subject to uncertainty. For incidence shifts in rank of up to twelve positions were observed. For prevalence, most diseases shifted maximally three or four places in rank. Conclusion: Estimates of incidence and prevalence can be obtained by combining data from GPRNs. Uncertainty in the estimates of absolute figures may lead to different rankings of diseases and, hence, should be taken into consideration when comparing disease incidences and prevalences.


Related Articles

  • Visit to general practitioners as a proxy for accessing chronic benefits by members of medical schemes, South Africa. Willie, Mncedisi M.; Gantsho, Monwabisi // African Journal of Primary Health Care & Family Medicine;2012, Vol. 4 Issue 1, p1 

    Background: Prescribed Minimum Benefits is a list of conditions that all medical schemes need to cover in full, and includes a select of chronic conditions. Chronic conditions affect people's lifestyles and require ongoing management over a period of years for long-term survival. Objectives:...

  • Influence of chronic comorbidity and medication on the efficacy of treatment in patients with diabetes in general practice. Wami, Welcome Mkululi; Buntinx, Frank; Bartholomeeusen, Stefaan; Goderis, Geert; Mathieu, Chantal; Aerts, Marc // British Journal of General Practice;Apr2013, Vol. 63 Issue 609, pe267 

    Background: Evidence on the influence of comorbidity and comedication on clinical outcomes in patients with type 2 diabetes mellitus is scarce. Aim: To ascertain the effect of five chronic diseases (joint disorder, respiratory disease, anaemia, malignancy, depression) and three chronically used...

  • GPs will be pressed harder over targets.  // Pulse;11/25/2002, Vol. 62 Issue 45, p3 

    Reports the pressure faced by general practitioners in improving targets for chronic diseases and rates of immunizations to meet the criteria for performance indicators in Great Britain.

  • Telehealth does not increase GP workload.  // PharmacoEconomics & Outcomes News;11/2/2013, Issue 690, p5 

    The article discusses the results of a study which appeared in an article by M Bardsley et al. in the October 8, 2013 issue of "BMC Health Services Research," revealing that the use of home-based telehealth for people with chronic disease does not modify rates of contact with general practices.

  • A wild gene chase. Coghlan, Andy // New Scientist;12/09/2000, Vol. 168 Issue 2268, p16 

    Reports on the Population Biomedical Collection project which is an attempt to link genes to diseases. Fear that British physicians will fail to link a patient's symptoms and phenotype and genotype genes; Cost of the project; Role of general practitioners in establishing histories of disease;...

  • EEC doctors meet in Dublin.  // British Medical Journal (Clinical Research Edition);12/12/1981, Vol. 283 Issue 6306, p1626 

    Focuses on the approval of the draft directive on general practitioners (GP) training by the Standing Committee of Doctors in Europe. Requirements for training of GP; Objectives of the standing committee; Introduction of health card for people with chronic disease.

  • Deaths decline with primary investment.  // New Zealand Doctor;8/13/2008, p7 

    The article reports on the results of a longitudinal research project relating to socially disadvantaged patients with chronic care conditions, which were presented at the Royal New Zealand College of General Practitioners Annual Scientific Conference held in Queenstown, New Zealand. Based on...

  • Referring patients to specialists: A structured vignette survey of Australian and British GPs. Jiwa, Moyez; Gordon, Michael; Arnet, Hayley; Hooi Ee; Bulsara, Max; Colwell, Brigitte // BMC Family Practice;2008, Vol. 9, Special section p1 

    Background: In Australia and in the United Kingdom (UK) access to specialists is sanctioned by General Practitioners (GPs). It is important to understand how practitioners determine which patients warrant referral. Methods: A self-administered structured vignette postal survey of General...

  • Impact of the new General Medical Services contract on the clinical laboratory. Smellie, WSA; Roy, DV // Annals of Clinical Biochemistry;Jan2005, Vol. 42 Issue 1, p4 

    The new General Medical Services contract that has been adopted in England and Wales, with similar contracts in Scotland and Northern Ireland, proposes far-reaching changes to the way in which general practitioners practise and are remunerated. This includes a range of quality indicators, which...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics