Demographic and microbial characteristics of extrapulmonary tuberculosis cases diagnosed in Malatya, Turkey, 2001-2007

Gunal, Selami; Zhenhua Yang; Agarwal, Mansi; Koroglu, Mehmet; Arıcı, Zeynep Kazgan; Durmaz, Riza
January 2011
BMC Public Health;2011, Vol. 11 Issue 1, p154
Academic Journal
Background: Extrapulmonary tuberculosis (EPTB) has an increasing rate in Turkey. The reason remains largely unknown. A better understanding of the demographic and microbial characteristics of EPTB in the Turkish population would extend the knowledgebase of EPTB and allow us to develop better strategies to control tuberculosis (TB). Methods: We retrospectively evaluated clinical and laboratory data of 397 bacteriologically-confirmed TB cases diagnosed during an eight year-period using by chi-square analysis and multivariate logistic regression model. Results: Of the 397 study patients, 103 (25.9%) had EPTB and 294 (74.1%) had pulmonary tuberculosis (PTB). The most commonly seen two types of EPTB were genitourinary TB (27.2%) and meningeal TB (19.4%). TB in bone/joints, pleural cavity, lymph nodes, skin, and peritoneal cavity occurred at a frequency ranging from 9.7% to 10.7%. The age distribution was significantly different (P < 0.01) between PTB and EPTB, with patients older than 45 years tending to have an increased risk of EPTB. Furthermore, the distribution of different types of EPTB differed significantly among age groups (P = 0.03). Meningeal and bone and/or joint TB were more commonly observed among the male patients, while lymphatic, genitourinary, and peritoneal TB cases were more frequently seen among females. Unique strain infection was statistically significantly associated with EPTB (OR: 2.82, 95% CI [1.59, 5.00]). Conclusions: EPTB accounted for a significant proportion of TB cases in Malatya, Turkey between 2001 and 2007. The current study has provided an insight into the dynamics of EPTB in Malatya, Turkey. However, the risk factors for having EPTB in Malatya, Turkey remain to be assessed in future studies using population-based or randomly selected sample.


Related Articles

  • Risk of tuberculosis and fuel use: a population study. Saha, Asim; Sharma, Y. K.; Kulkarni, P. K.; Saiyed, H. N. // Occupational & Environmental Medicine;Dec2011, Vol. 68 Issue 12, p934 

    This article discusses a study which examined the effect of fuel use on the occurrence of tuberculosis. The study was conducted in an Indian village and involved 442 individuals who were randomly selected, interviewed and subjected to medical examination. Researchers utilized the logistic...

  • Factors associated with low cure rate of tuberculosis in remote poor areas of Shaanxi Province, China: a case control study. Xianqin Ai; Ke Men; Liujia Guo; Tianhua Zhang; Yan Zhao; Xiaolu Sun; Hongwei Zhang; Guangxue He; van der Werf, Marieke J.; van den Hof, Susan // BMC Public Health;2010, Vol. 10 Issue 1, p112 

    Background: The directly observed therapy-short course (DOTS) strategy was introduced in Shaanxi province, China to improve tuberculosis (TB) control by means of improved case detection (target: > = 70%) and treatment success rates (target: > = 85%) in new smear positive (SS+) TB patients. At a...

  • Selecting a Variable for Predicting the Diagnosis of PTB Patients From Comparison of Chest X-ray Images. Rijal, Omar Mohd.; Noor, Norliza Mohd.; Shee Lee Teng // Journal of Applied Sciences;2008, Vol. 8 Issue 7, p1293 

    A statistical method of comparing two digital chest radiographs for Pulmonary Tuberculosis (PTB) patients has been proposed. After applying appropriate image registration procedures, a selected subset of each image is converted to an image histogram (or box plot). Comparing two chest X-ray...

  • Prevalence and Risk Factors of Drug-Resistant Tuberculosis Along the Mexico--Texas Border. Taylor, Jeffery P.; Suarez, Lucina // American Journal of Public Health;Feb2000, Vol. 90 Issue 2, p271 

    OBJECTIVES: This study determined factors associated with drug resistance among 3496 patients with tuberculosis who resided in Texas counties along the Mexican border. METHODS: Univariate and logistic regression analyses were performed to identify risk factors associated with drug resistance....

  • Relative effectiveness of Irish factories in the surveillance of slaughtered cattle for visible lesions of tuberculosis, 2005-2007. Olea-Popelka, Francisco; Freeman, Zach; White, Paul; Costello, Eamonn; O'Keeffe, James; Frankena, Klaas; Martin, Wayne; More, Simon // Veterinary Ireland Journal;Jun2012, Vol. 2 Issue 6, p1 

    Background: In Ireland, every animal is examined at slaughter for its fitness for human consumption. The aim of this study was to determine the relative effectiveness of factories in submitting and subsequently in having suspect lesions confirmed as bovine tuberculosis (TB) lesions during the...

  • Determinants of health system delay among confirmed tuberculosis cases in Spain. Díez, M.; Bleda, M. J.; Alcaide, J.; Castells, C.; Cardenal, J. I.; Domínguez, A.; Gayoso, P.; Guitiérrez, G.; Huerta, C.; López, M. J.; Moreno, T.; Muñoz, F.; García-Fulgueiras, A.; Picó, M.; Pozo, F.; Quirós, J. R.; Robles, F.; Sánchez, J. M.; Vanaclocha, H.; Vega, T. // European Journal of Public Health;Aug2005, Vol. 15 Issue 4, p343 

    Background: Health system delay (HSD) is an important issue in tuberculosis (TB) control. This report investigates HSD and associated factors in a cohort of Spanish culture-confirmed TB patients. Methods: Data were collected from clinical records. Using logistic regression with two different...

  • The relationship between (stigmatizing) views and lay public preferences regarding tuberculosis treatment in the Eastern Cape, South Africa. Cramm, Jane M.; Nieboer, Anna P. // International Journal for Equity in Health;2011, Vol. 10 Issue 1, p1 

    Background: Tuberculosis (TB) and human immune virus/acquired immune deficiency syndrome (HIV/AIDS) stigmas affect public attitudes toward TB treatment and policy. This study examined 'stigmatizing' ideas and the view that 'TB patients should line-up in the chronic illness queue' in relation to...

  • Determinants of Pulmonary Tuberculosis among Inmates at Mangaung Maximum Correctional Facility in Bloemfontein, South Africa. Nyasulu, Peter; Mogoere, Serame; Umanah, Teye; Setswe, Geoffrey // Tuberculosis Research & Treatment;3/17/2015, Vol. 2015, p1 

    Introduction. Correctional facilities house large number of inmates who are at high risk of developing tuberculosis (TB); however factors associated with TB among inmates at Mangaung Correctional Centre have not been studied. Study Population and Methods. We undertook a case control study and...

  • A Bayesian approach to study the risk variables for tuberculosis occurrence in domestic and wild ungulates in South Central Spain. Rodr¡guez-Prieto, V¡ctor; Mart¡nez-L¢pez, Beatriz; Barasona, Jos‚ µngel; Acevedo, Pelayo; Romero, Beatriz; Rodriguez-Campos, Sabrina; Gort zar, Christian; S nchez-Vizca¡no, Jos‚ Manuel; Vicente, Joaqu¡n // BMC Veterinary Research;2012, Vol. 8 Issue 1, p148 

    Background: Bovine tuberculosis (bTB) is a chronic infectious disease mainly caused by Mycobacterium bovis. Although eradication is a priority for the European authorities, bTB remains active or even increasing in many countries, causing significant economic losses. The integral consideration of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics