Leptin Resistance May Help Ward Off ARDS, ALI

March 2011
Pulmonary Reviews;Mar2011, Vol. 16 Issue 3, p5
The article reports on the possible help afforded by leptin resistance, a key protein in metabolism and appetite regulation, in preventing acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) in type II diabetes mellitus patients. Based on a study, severity of ARDS and ALI may be prevented or lessened with the development of therapies that increase leptin resistance. The normal effects of leptin are reportedly mediated in the brain and drugs not delivered to the brain are relatively easy to develop.


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