One cell to heal them all
Tags: STEM cells; CARTILAGE; TENDONS
Related Articles
- Characterization of differential properties of rabbit tendon stem cells and tenocytes. Jianying Zhang; Wang, James H-C // BMC Musculoskeletal Disorders;2010, Vol. 11, Special section p1
Background: Tendons are traditionally thought to consist of tenocytes only, the resident cells of tendons; however, a recent study has demonstrated that human and mouse tendons also contain stem cells, referred to as tendon stem/progenitor cells (TSCs). However, the differential properties of...
- Mesenchymal Stem Cell Therapy Regenerates the Native Bone-Tendon Junction after Surgical Repair in a Degenerative Rat Model. Nourissat, Geoffroy; Diop, Amadou; Maurel, Nathalie; Salvat, Colette; Dumont, Sylvie; Pigenet, Audrey; Gosset, Marjolaine; Houard, Xavier; Berenbaum, Francis // PLoS ONE;2010, Vol. 5 Issue 8, p1
Background: The enthesis, which attaches the tendon to the bone, naturally disappears with aging, thus limiting joint mobility. Surgery is frequently needed but the clinical outcome is often poor due to the decreased natural healing capacity of the elderly. This study explored the benefits of a...
- Stem cells expressing SMAD 8: a platform for tendon regeneration. // Molecular Therapy;May2004 Supplement 1, Vol. 9, p147
An abstract of the article "Stem Cells Expressing SMAD 8: A Platform for Tendon Regeneration," by Gadi Pelled, Andrea Hoffman, Gadi Turgeman, Peter Eberle, Yoram Zilberman, Hadassah Shinar, Keren Keinan-Adamsky, Andreas Winkel, Gil Navon, Gerhard Gross, and Dan Gazit is presented.
- Characteristics of Stem Cells Derived from the Degenerated Human Intervertebral Disc Cartilage Endplate. Lan-Tao Liu; Bo Huang; Chang-Qing Li; Ying Zhuang; Jian Wang; Yue Zhou // PLoS ONE;2011, Vol. 6 Issue 10, p1
Mesenchymal stem cells (MSCs) derived from adult tissues are an important candidate for cell-based therapies and regenerative medicine due to their multipotential differentiation capability. MSCs have been identified in many adult tissues but have not reported in the human intervertebral disc...
- Tendon Regeneration and Repair with Adipose Derived Stem Cells. Uysal, A. Cagri; Mizuno, Hiroshi // Current Stem Cell Research & Therapy;Jun2010, Vol. 5 Issue 2, p161
Tendon, the crucial element of the musculoskeletal system, when damaged, never restores the biological and biomechanical properties completely. Recently, tissue engineering and regenerative medicine have enabled the differentiation of postnatal somatic stem cells or mesenchymal stem cells (MSCs)...
- Bone Marrow-Derived Mesenchymal Stem Cells Influence Early Tendon-Healing in a Rabbit Achilles Tendon Model. Chong, Alphonsus K. S.; Ang, Abel D.; Gob, James C. H.; Hui, James H. P.; Lim, Aymeric Y. T.; Beng Hai Lim // Journal of Bone & Joint Surgery, American Volume;Jan2007, Vol. 89 Issue 1, p74
Background: A repaired tendon needs to be protected for weeks until it has accrued enough strength to handle physiological loads. Tissue-engineering techniques have shown promise in the treatment of tendon and ligament defects. The present study tested the hypothesis that bone marrow-derived...
- Implication of NOD1 and NOD2 for the Differentiation of Multipotent Mesenchymal Stem Cells Derived from Human Umbilical Cord Blood. Hyung-Sik Kim; Tae-Hoon Shin; Se-Ran Yang; Min-Soo Seo; Dong-Jae Kim; Soo-Kyung Kang; Jong-Hwan Park; Kyung-Sun Kang // PLoS ONE;2010, Vol. 5 Issue 10, p1
Toll-like receptors (TLRs) and Nod-like receptors (NLRs) are known to trigger an innate immune response against microbial infection. Although studies suggest that activation of TLRs modulate the function of mesenchymal stem cells (MSCs), little is known about the role of NLRs on the MSC...
- IMPORTANCE OF STEM CELLS IN DENTISTRY. Shruthi, M.; Kumar, Ashok S.; Annapurna, P. D. // Annals & Essences of Dentistry;Apr-Jun2012, Vol. 4 Issue 2, p75
Stem-cells are primitive cells which are present in different parts of the body such as bones, umbilical cord, placenta, embryo, teeth etc. For years scientists all over the world have been working on possibilities of using these Stem-cells to regenerate human cells which are damaged due to...
- Hypoxia mediated isolation and expansion enhances the chondrogenic capacity of bone marrow mesenchymal stromal cells. Adesida, Adetola B.; Mulet-Sierra, Aillette; Jomha, Nadr M. // Stem Cell Research & Therapy;2012, Vol. 3 Issue 2, p1
Introduction: The capacity of bone marrow mesenchymal stromal cells (BMSCs) to be induced into chondrocytes has drawn much attention for cell-based cartilage repair. BMSCs represent a small proportion of cells of the bone marrow stromal compartment and, thus, culture expansion is a necessity for...
