TITLE

Preeklamptik gebe kadınlarda intratekal olarak uygulanan levobupivakain ve bupivakainin etkinliğinin karşılaştırılması

AUTHOR(S)
Bali, Nihat; Karaman, Haktan; Tüfek, Adnan; Kavak, Gönül Ölmez; Yıldırım, Zeynep Baysal; Cengiz, Mustafa
PUB. DATE
March 2011
SOURCE
Dicle Medical Journal / Dicle Tip Dergisi;2011, Vol. 38 Issue 1, p19
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: The aim of this study was to compare the efficacy and side effects of levobupivacaine and bupivacaine in pre-eclamptic patients that will undergo caesarean section by spinal anesthesia. Materials and methods: Preeclamptic, 18-45 years-old patients that will undergo a caesarean section were included in the study in a prospective randomized manner. They were separated into two groups: Group B, intrathecally received 2 mL 0.5% bupivacaine (10 mg), while Group L intrathecally received 2 mL 0.5% levobupivacaine (10 mg). Blood pressure and heart rates of the patients were measured and recorded at 3, 6, 9, 12, 15th minutes and thereafter, every 5 minutes during operation. The evaluations were done through the comparison of patient's and surgeon's satisfaction between the groups. Visual analog score (VAS) was used for comparison. Results: Systolic arterial pressure values at 3, 15, 35 and 40th minutes in Group B were significantly lower than those in Group R (p<0.05), no significant difference was found in heart rates. Group B more frequently developed hypotension (10 patients versus 15 patients), so significantly greater amount efedrin was needed to treat hypotension (p=0.012). Patient satisfaction was recorded high in favor of Group L (p=0.011), however no difference was found in surgeon satisfaction between two groups (p>0.05). Conclusion: Intrathecal levobupivacaine for spinal anesthesia ensured a more stable hemodynamics but both local anesthesia enabled a sufficient and adequate surgical anesthesia in pre-eclamptic patients.
ACCESSION #
59310918

 

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