TITLE

The 2009 H1N1 Strain Could Lead to the Development of a Universal Influenza Vaccine

PUB. DATE
February 2011
SOURCE
Pulmonary Reviews;Feb2011, Vol. 16 Issue 2, p10
SOURCE TYPE
Periodical
DOC. TYPE
Article
ABSTRACT
The article reports that patients who were infected with the H1N1 virus in 2009 may have developed protective antibodies that would help in the creation of a wide-spectrum flu vaccine. A study published in the January 17, 2011 issue of the "Journal of Experimental Medicine" confirms that isolated antibodies from test subjects with the 2009 H1N1 virus contained genes that could counter various flu strains including seasonal H1N1, the 1918 "Spanish flu," and the H5N1 avian flu.
ACCESSION #
58776129

 

Related Articles

  • Influenza and its challenge:A Review. Abhinaba Ghosh; Mohanasrinivasan, V.; Devi, C.Subathra // Journal of Pharmacy Research;Oct2010, Vol. 3 Issue 10, p2533 

    Influenza has been a disease of great concern since the Spanish Influenza pandemic of 1918-1919.It continues to be a menace in many parts of the world including some parts of Asia. It is a zoonotic disease capable of transmitting among humans with a high fatality rate of about 63%.Because of...

  • Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A Randomised Trial. Bethell, Delia; Saunders, David; Jongkaewwattana, Anan; Kramyu, Jarin; Thitithayanont, Arunee; Wiboon-ut, Suwimon; Yongvanitchit, Kosol; Limsalakpetch, Amporn; Kum-Arb, Utaiwan; Uthaimongkol, Nichapat; Garcia, Jean Michel; Timmermans, Ans E.; Peiris, Malik; Thomas, Stephen; Engering, Anneke; Jarman, Richard G.; Mongkolsirichaikul, Duangrat; Mason, Carl; Khemnu, Nuanpan; Tyner, Stuart D. // PLoS ONE;Mar2013, Vol. 8 Issue 3, p1 

    Introduction: Recent studies have demonstrated that inactivated seasonal influenza vaccines (IIV) may elicit production of heterosubtypic antibodies, which can neutralize avian H5N1 virus in a small proportion of subjects. We hypothesized that prime boost regimens of live and inactivated...

  • Broad Antibodies to H1N1: Pandemic to Pan-Vaccine? Breindl, Anette // BioWorld Today;1/14/2011, Vol. 22 Issue 10, p1 

    The article discusses research on antibodies against multiple strains of influenza. It references a study by Patrick Wilson and Rafi Ahmed, published in the January 10, 2010 issue of the "Journal of Experimental Medicine." The study discovered that seasonal H1N1 strain and H5N1 avian flu are...

  • H1N1 And H5N1 Update.  // Thailand Tourism Report;Q1 2010, p30 

    The article offers an update about H1N1 and H5N1 flu virus outbreaks as of the first quarter of 2010. It reports that 4,735 people died globally in December and concern about the availability and effectiveness of influenza vaccine Tamiflu remains. Meanwhile, there is a cited improvement in the...

  • Molecular docking analysis of 2009-H1N1 and 2004-H5N1 influenza virus HLA-B*4405-restricted HA epitope candidates: implications for TCR cross-recognition and vaccine development. Su, Chinh TT; Schönbach, Christian; Kwoh, Chee-Keong // BMC Bioinformatics;2013, Vol. 14 Issue Suppl 2, p1 

    Background: The pandemic 2009-H1N1 influenza virus circulated in the human population and caused thousands deaths worldwide. Studies on pandemic influenza vaccines have shown that T cell recognition to conserved epitopes and cross-reactive T cell responses are important when new strains emerge,...

  • Protection from the 2009 H1N1 Pandemic Influenza by an Antibody from Combinatorial Survivor-Based Libraries. Kashyap, Arun K.; Steel, John; Rubrum, Adam; Estelles, Angeles; Briante, Raffaella; Ilyushina, Natalia A.; Li Xu; Swale, Ryann E.; Faynboym, Aleksandr M.; Foreman, Pamela K.; Horowitz, Michael; Horowitz, Lawrence; Webby, Richard; Palese, Peter; Lerner, Richard A.; Bhatt, Ramesh R. // PLoS Pathogens;Jul2010, Vol. 6 Issue 7, p1 

    Influenza viruses elude immune responses and antiviral chemotherapeutics through genetic drift and reassortment. As a result, the development of new strategies that attack a highly conserved viral function to prevent and/or treat influenza infection is being pursued. Such novel broadly acting...

  • Recommended viruses for influenza vaccines for use in the 2010-2011 northern hemisphere influenza season.  // Weekly Epidemiological Record;3/5/2010, Vol. 85 Issue 10, p81 

    The article focuses on the recommended viruses for inclusion in influenza vaccines for the northern and southern hemispheres for the 2010-2011 season. An overview of influenza between September 2009 and January 2010 covering various regions, including Africa, the Americas, Europe and Asia, is...

  • Antigenic and genetic characteristics of zoonotic influenza viruses and development of candidate vaccine viruses for pandemic preparedness.  // Weekly Epidemiological Record;10/19/2012, Vol. 87 Issue 42, p401 

    The article discusses the genetic and antigenic characterization of influenza viruses under consideration for preparation of vaccines. The article discusses the activity of Influenza A(H5N1), Influenza A(H9N2)and Influenza A(H3N2)v between 23 February to 18 September 2012, amongst others....

  • Characterization of cross protection of Swine-Origin Influenza Virus (S-OIV) H1N1 and reassortant H5N1 influenza vaccine in BALB/c mice given a single-dose vaccination. Lin, Hui-Tsu; Chuang, Chuan-Chang; Wu, Hsieh-Ling; Chu, Der-Ming; Wang, Yeau-Ching // Journal of Biomedical Science;2013, Vol. 20 Issue 1, p1 

    Background: Influenza virus has antigen drift and antigen shift effect, vaccination with some influenza vaccine might not induce sufficient immunity for host to the threat of other influenza virus strains. S-OIV H1N1 and H5N1 influenza vaccines in single-dose immunization were evaluated in mice...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics