TITLE

GENTIUM COMPLETES PRECLINICAL/CLINICAL DEFIBROTIDE STUDIES

PUB. DATE
March 2011
SOURCE
Worldwide Biotech;Mar2011, Vol. 23 Issue 3, p1
SOURCE TYPE
Trade Publication
DOC. TYPE
Article
ABSTRACT
The article provides information on a drug developed by Gentium S.p.A. in Italy, called defibrotide, for the prevention and treatment of veno-occlusive disease (VOD), a life threatening condition of the liver that occur when a patient undergoes stem cell transplant. A detailed description of VOD is provided. In the research study led by Gentium Scientific director Massimo Iacobelli, the drug is reported to have no side effects on rats and healthy human volunteers, while pregnant rats showed maternal toxicity and intrauterine development of the progeny.
ACCESSION #
58691936

 

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