Kronik Hasta Servislerinde Uzun Süre Yatan Şizofreni Hastaları Nasıl Tedavi Ediliyor?

Kurt, Erhan; Özver, ‹smail; Alataş, Gazi; Bilgiç, Vedat
July 2010
Yeni Symposium;2010, Vol. 48 Issue 3, p223
Academic Journal
Objective: With this study , the evaluation of their treatment of patients with schizophreniawho have been hospitalized for a long time in the chronic psychiatric patients services in Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery was aimed. Method: The medical records of 296 patients with schizophrenia in the chronic psychiatric inpatient units have been retrospectively and sociodemographic properties, antipsychotic prescriptions and medication combinations of these patients have been examined. Findings: The duration of hospitalization of the 296 patients with schizophrenia were ranging between 1 and 36 years (16.0±10.2 years). They were using 13 different antipsychotics prescribed as monotherapy or in combination with another antipsychotic. Among the atypical antipsychotics (AAPs) clozapine was the most preferred one whereas fluphenazine was the most prescribed among depot antipsychotics and haloperidol and chlorpromazine were the most used among classic antipsychotics (CAPs). Additionally 23 patients (7.8%) were not using any antipsychotic medications. Of the 273 patients who underwent antipsychotic medication, the 144 (48.8%) were taking antipsychotic monotherapy and 129 (43%) were on a combination therapy with two or more antipsychotic drugs. The most frequent combination in the latter group was haloperidol and chlorpromazine combination. It was also interesting that 29 patients (10%) were under triple antipsychotic medication. 42 patients (14%) were using depot antipsychotic in combination with AAPs or CAPs. 40 patients (13.5%) were using one or more CAPs or AAPs together whereas 209 patients (70.3%) were using one or more CAPs and 108 (36.5%) patients were using one or more AAPs. 49 (16.6%) patients were using mood stabilizers or anticonvulsants, 8 (2.7%) patients were using antidepressants, and 53 (17.9%) were using benzodiazepines whereas 209 (70.6%) patients were using anticholinergics. Discussion and Conclusion: The examination of the treatment regimens of the schizophrenic patients who have been hospitalized 16 years in average in the biggest and the oldest mental disorder hospital in our country provided us important data on this topic. Future researches as a continuum of this study are needed. Especially measuring the effects and the side effects of drugs and comparing CAPs and AAPs in respect to these measurements may provide more detailed data.


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