TITLE

Effect of Abnormal Fasting Plasma Glucose Level on All-Cause Mortality in Older Patients With Acute Myocardial Infarction: Results From the Beijing Elderly Acute Myocardial Infarction Study (BEAMIS)

AUTHOR(S)
Shi-Wei Yang; Yu-Jie Zhou; Xiao-Min Nie; Yu-Yang Liu; Jie Du; Da-Yi Hu; De-An Jia; Fet Gao; Bin Hu; Zhe Fang; Hong-Ya Han; Xiao-Li Liu; Zhen-Xian Yan; Jian-Long Wang; Qi Hua; Yu-Jie Shi; Hong-Wet Li
PUB. DATE
February 2011
SOURCE
Mayo Clinic Proceedings;Feb2011, Vol. 86 Issue 2, p94
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVE: To assess whether the relationship between abnormal fasting plasma glucose (FPG) levels and patient outcomes holds for both older men and older women with acute myocardial infarction (AMI). PATIENTS AND METHODS: From April 1, 2004, to October 31, 2006, a total of 2016 consecutive older patients (age ≥65 years) presenting with AMI were screened. Of these patients, 1854 were consecutively enrolled in the study. Patients were categorized into 4 groups: the hypoglycemic group (FPG, ≤90.0 mg/dL [to convert to mmol/L, multiply by 0.0555]; n=443, 23.9%), the euglycemic group (FPG, 90.1-126.0 mg/dL; n=812, 43.8%), the mildly hyperglycemic group (FPG, 126.1-162.0 mg/dL; n=308, 16.6%), and the severely hyperglycemic group (FPG, ≥162.1 mg/dL; n=291, 15.7%). The primary outcomes were rates of in-hospital and 3-year mortality. RESULTS: Female patients were older and had a higher incidence of diabetes mellitus but lower rates of smoking and use of invasive therapy. Men tended to have a higher frequency of hypoglycemia, whereas women tended to have a higher frequency of hyperglycemia. No significant difference was found in in-hospital (10.9% vs 9.1%; P=.36) or 3-year (24.5% vs 24.5%; P=.99) mortality between male and female patients, and FPG-associated mortality did not vary significantly by sex. CONCLUSION: An increased FPG level was associated with a relatively higher risk of in-hospital mortality in men but not in women. Nonetheless, increased and decreased FPG levels at admission could predict higher mortality rates regardless of sex. There was a striking U-shaped relationship between FPG levels and in-hospital and 3.year mortality. The effect of abnormal FPG level on out- comes among older patients with AMI did not vary significantly by sex.
ACCESSION #
58103780

 

Related Articles

  • Descriptive Epidemiology of Cases of Acute Myocardial Infarction in Tobago. Alfred, R.; Okeke, O.; Moronu, C.; Elliot, V.; Frankson, A.; Barton, E. N. // West Indian Medical Journal;Jun2009, Vol. 58 Issue 3, p257 

    Objectives: The goal of this study is to identify co-morbidities associated with acute myocardial infarction in Tobago. Methods: This was a longitudinal retrospective study of myocardial infarction at the Tobago Regional Hospital in two selected periods: January 2007 to April 2007 and January...

  • Myocardial infarction Associated with Recency of Immigration to Ontario. Saposnik, G.; Redelmeier, D. A.; Lu, H.; Fuller-Thomson, E.; Lonn, E.; Ray, J. G. // QJM: An International Journal of Medicine;Apr2010, Vol. 103 Issue 4, p253 

    Background: New immigrants to North America exhibit lower rates of obesity and hypertension than their native-born counterparts. Whether this is reflected by a lower relative risk of acute myocardial infarction (AMI) is not known. Objective: To determine the risk of AMI among new immigrants...

  • Basic Science -- Complications and Comorbidities.  // Current Medical Literature: Diabetes;2008, Vol. 25 Issue 1, p19 

    The article discusses several studies done concerning complications and comorbidities of diabetes, published in different journals. These include vessel wall stiffness in type 1 diabetes and the hemodynamic effects of acute hypoglycemia, prosclerotic effects of monocyte chemoattractant protein-1...

  • Post-heart attack harder for women.  // Active Living;Jan2012, Vol. 21 Issue 1, p25 

    The article offers information on a Heart and Stroke Foundation-funded study which indicates that female heart attack victims below age 55 experience more severe chest pains and worse quality of life after the attack.

  • From hypoglycemia to right heart infarction: treatment of hypoglycemia in type 1 diabetes. Bačun, Tatjana; Kibel, Aleksandar; Jelić, Krešimir; Pavić, Roman; Degmečić, Dunja; Sidorov, Dajana // Medicinski Glasnik;Aug2012, Vol. 9 Issue 2, p402 

    This case report presents a young 30-year old male patient with type 1 diabetes mellitus, who was treated for hypoglycemia and a general bad feeling. He was somnolent, pale, sweaty, hypotensive (65/40 mmHg) with bradycardia (40 beats per min) and additional workup revealed right myocardial...

  • Silent myocardial infarction during hypoglycemic coma. Mahajan, Varun Vijay; Dogra, Vikas; Pargal, Iesha; Singh, Navtej // Indian Journal of Endocrinology & Metabolism;Jan2012, Vol. 16 Issue 1, p139 

    Hypoglycemia is a common complication of treatment of diabetes mellitus. The potential neurological complications of hypoglycemia as seizures and coma are well-recognized entities. A hypoglycemic episode is a risk factor for a patient with diabetes to have cardiovascular complications....

  • FREQUENCY OF CONVENTIONAL RISK FACTORS OF MYOCARDIAL INFARCTION IN GULAB DEVI CHEST HOSTPITAL. IQBAL, U. J.; KALEEM, M.; IQBAL, N.; HANIF, M. I.; HANIF, A. // Biomedica;Sep2014, Vol. 30 Issue 3, p1 

    Background: Acute myocardial infarction (M.I) is potentially critical and the most common cardiac emergency presenting to a hospital. Having significant mortality and morbidity cardiovascular risk factors are on the rise in Pakistan. In view of the associated lower survival ischemic heart...

  • Unhealthy lifestyles make our doctors' blood boil. McManus, Gerard // Management Today (14405636);Nov/Dec2013, p44 

    The article reports on the cases of heart attack in Australia along with decline in death caused due to heart attack in the country. Topics include symptoms of heart attack such as nausea, cold sweat and shortness of breath; risk factors for heart attack such as smoking, diabetes and depression;...

  • A national analysis of complications following hemiarthroplasty for hip fracture in older patients. Jameson, S.S.; Khan, S.K.; Baker, P.; James, P.; Gray, A.; Reed, M.R.; Deehan, D.J. // QJM: An International Journal of Medicine;May2012, Vol. 105 Issue 5, p455 

    Background: There is emerging evidence that patients with fractured neck of femur (FNOF) aged >85 years have different demands on a health-care system when compared to younger patients.Aim: We sought to better quantify this in terms of comorbidity and complication rates.Design: Retrospective...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics