TITLE

Conservative Management of Pituitary Macroadenoma Contacting the Optic Apparatus

AUTHOR(S)
Ryu, Won Hyung A.; Tam, Samantha; Rotenberg, Brian; Labib, Mohamed Ahmed; Lee, Donald; Nicolle, David A.; Van Uum, Stan; Duggal, Neil
PUB. DATE
November 2010
SOURCE
Canadian Journal of Neurological Sciences;Nov2010, Vol. 37 Issue 6, p837
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: To describe the tumor characteristics and visual function in conservatively managed patients with non-functioning pituitary macroadenoma (NFMA) that contacted/compressed the visual pathway. Design: Retrospective case-series. Setting: Tertiary-care academic institution. Participants: Six patients with diagnosis of NFMA. Main Outcome: Visual function and radiological characteristics of the optic apparatus and pituitary tumor. Results: All patients had radiological evidence of optic apparatus compression but only one had visual field defect at the initial presentation. While two of the six patients developed visual field changes during followup (41±34.8 months), the patient with visual field defect at the time of diagnosis improved to normal vision. Conclusions: Select NFMAs that contact the optic apparatus, without visual dysfunction, may be managed with close ophthalmological and radiographic monitoring, depending on tumor and imaging characteristics. This may be of particular relevance in patients considered to have a high peri-operative risk, such as advanced age or significant co-morbidities.
ACCESSION #
57949619

 

Related Articles

  • Topographic variations of the optic chiasm and the foramen diaphragma sellae. Hyung-Sun Won; Seung-Ho Han; Chang-Seok Oh; Jung-Il Lee; In-Hyuk Chung; Sun Ho Kim // Surgical & Radiologic Anatomy;Aug2010, Vol. 32 Issue 7, p653 

    Pituitary adenomas can expand upward through the foramen diaphragma sellae (FDS), compress the visual pathways on the suprasellar region, and cause diverse visual defects. However, the relationship between the FDS and the visual pathway has not been thoroughly clarified. This study was thus...

  • Glaucoma or Benign Tumor? Fanelli, James L. // Review of Optometry;Feb2010, Vol. 147 Issue 2, p111 

    The article presents a case study of an 81-year-old white female presented with visual field changes that were suggestive of a conversion to glaucoma. She was medicated with several medicines including restasis, atenolol, and lipitor. A magnetic resonance imaging (MRI) was conducted which...

  • Managing Prolactinoma during Pregnancy. Azar, Maziar; Nikoobakht, Mehdi // Journal of Family & Reproductive Health;2010, Vol. 4 Issue 2, p83 

    Objective: Prolactinomas are the most common pituitary tumors in pregnant women. We conducted this study on pregnant women with prolactinoma to determine their clinical symptoms and signs and eventual necessity to medical therapy. Materials and methods: A descriptive study was performed on 85...

  • Retrospective Comparison of an Endoscopic Assisted versus a Purely Endoscopic Approach to Sellar Tumour Resection. Minet, Wyatt W.; Sommer, Doron D.; Yousuf, Kashif; Midia, Mehran; Farrokhyar, Forough; Reddy, Kesava // Journal of Otolaryngology -- Head & Neck Surgery;Dec2008, Vol. 37 Issue 6, p759 

    Introduction: The purely endoscopic approach to sellar tumors is thought to offer improved visualization and decreased complications compared to the endoscopic assisted approach. Methods: This retrospective study was approved by the Research Ethics Board (REB) of McMaster University. Seventy-one...

  • Untethering of herniated left optic nerve after dopamine agonist treatment for giant prolactinoma. Gkekas, Nikolaos; Primikiris, Panagiotis; Georgakoulias, Nikolaos // Acta Neurochirurgica;Mar2013, Vol. 155 Issue 3, p495 

    The article discusses the chiasm herniation of optic nerve after dopamine agonist treatment for macroprolactinomas and giant prolactinomas. It presents a medical case of a patient with right-eye blindness and progressive deterioration of his left-eye visual field, while being on dopamine agonist...

  • Managing primary pituitary tumours: Assessments and complications. Mestecky, Ann-Marie // British Journal of Neuroscience Nursing;Jun/Jul2010, Vol. 6 Issue 5, p222 

    Specific treatment for primary pituitary tumours and the diseases they cause will depend on the tumour type, but most patients require surgery which is most commonly performed via a transnasal transsphenoidal approach. Postoperative complications include impairment of visual acuity, visual field...

  • OPTOCHIASMATIC SYNDROME: ASSESSING OPTIC NERVE CHANGES BY OPTICAL COHERENCE TOMOGRAPHY. A CASE REPORT. Demea, H.; Demea, S.; Silaghi, A.; Silaghi, H. // Acta Endocrinologica (1841-0987);2015, Vol. 11 Issue 3, p363 

    Context. Optical Coherence Tomography (OCT) is a non-invasive diagnostic imaging technique, providing histological-like, high resolution transverse-section images of the eye structures. Objective. To quantify optic nerve's alterations in optochiasmatic syndrome by OCT and with a classical...

  • Full Endoscopic Transsphenoidal Surgery for Pituitary Adenoma-emphasized on Surgical Skill of Otolaryngologist. Fan, Yun-ping; Lv, Ming-hui; Feng, Shao-yan; Fan, Xiang; Hong, Hai-yu; Wen, Wei-ping; Li, Hua-bin // Indian Journal of Otolaryngology & Head & Neck Surgery;Jan2014 Supplement, Vol. 66, p334 

    The purpose is to summarize the experience in full endoscopic transsphenoidal resection of pituitary adenoma in 28 patients by rhinologist, and introduce the surgical skill of otolaryngologist, especially skills and cautions when operating inside nose. We removed pituitary adenoma in 28 patients...

  • Visual field assessment. Davies, Leon // Optometry Today;8/8/2015, Vol. 55 Issue 16, p48 

    A quiz concerning visual field assessment to test knowledge about visual pathway and indices generated by visual field instruments is presented.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics