Unexpected death of a young woman: is myocardial bridging significant?-A case report and review of literature

Sunnassee, Ananda; Zhu Shaohua; Ren Liang; Liu Liang
March 2011
Forensic Science, Medicine & Pathology;Mar2011, Vol. 7 Issue 1, p42
Academic Journal
Myocardial bridging (MB) refers to a congenital condition where a segment of a major coronary artery courses within the myocardium for a variable distance, and has been reported as an incidental finding in many cases. However, in some situations it has been shown to be associated with acute coronary syndromes, arrhythmias, myocardial ischemia and sudden death. We present the case of a 26-year-old Chinese woman with no previous history of disease who died unexpectedly in hospital. She had a 'common cold' with its associated symptoms. Autopsy revealed the presence of MB of the left anterior descending artery and microscopic examination showed associated cardiac lesions such as contraction band necrosis and interstitial fibrosis in the region supplied by the embedded artery. The coronaries were otherwise patent. Gross and microscopic examination of other organs was unremarkable. Toxicological analysis of body fluids and stomach content excluded death due to either drug intoxication or known poisonous substances. MB could have been responsible for death, but the disparate attitudes towards this phenomenon made this assumption open to discussion. We provide the case description and a short review of the literature on fatal and near- fatal cases involving MB.


Related Articles

  • Coronary Arteries in Crisscross Heart. Angelini, Paolo; Lopez, Alberto; Lufschanowski, Roberto; Nemeth, Margit A.; Flamm, Scott D. // Texas Heart Institute Journal;2003, Vol. 30 Issue 3, p208 

    Crisscross heart, or superoinferior ventricles, is a complex and often confusing congenital anomaly. We report a heretofore unreported presentation of "isolated" crisscross heart, in situs inversus levocardia, which allows us to more clearly define the typical features of crisscross ventricles....

  • Two Cases of Apical Ballooning Syndrome Masking Apical Hypertrophic Cardiomyopathy. Roy, Ranjini Raina; Hakim, Fayaz A.; Todd Hurst, R.; Simper, David; Appleton, Christopher P. // Texas Heart Institute Journal;2014, Vol. 41 Issue 2, p179 

    Apical akinesis and dilation in the absence of obstructive coronary artery disease is a typical feature of stress-induced (takotsubo) cardiomyopathy, whereas apical hypertrophy is seen in apical-variant hypertrophic cardiomyopathy. We report the cases of 2 patients who presented with takotsubo...

  • The perspective of ventricular noncompaction as seen by a nonagenarian. Lurie, Paul R. // Cardiology in the Young;Jun2008, Vol. 18 Issue 3, p243 

    The persistence of so-called spongy myocardium was first reported in humans in the 1960s. Subsequently, a few reports described the condition, utilizing inconsistent facts and terminology. In 1990 the first report appeared using the term ''noncompaction'', and detailed its clinical implications....

  • Cor triatriatum sinistrum: a rare congenital cardiac anomaly presenting in an elderly man with coronary artery disease. G�/4rb�/4z, Ali; �zbek, Cengiz; Yetkin, Ufuk; �zel�i, Ahmet; Bademci, Mehmet; Y�/4rekli, Ismail // Internet Journal of Thoracic & Cardiovascular Surgery;2009, Vol. 13 Issue 2, p3 

    Cor triatriatum sinistrum is a rare congenital cardiac anomaly in which a fibromuscular membrane divides the left atrium. We describe a case of cor triatriatum sinistrum: a rare congenital cardiac anomaly presenting in an elderly man with coronary artery disease. Diagnosis is usually achieved by...

  • Anomalous aortic origin of a coronary artery in siblings with Marfan syndrome. Brothers, Julie A.; Harris, Matthew A.; Paridon, Stephen M. // Cardiology in the Young;04/01/2011, Vol. 21 Issue 2, p238 

    We report a case of two brothers with Marfan syndrome and coexistent anomalous aortic origin of a coronary artery from the wrong sinus of Valsalva. To our knowledge, this is the first ever report of siblings with Marfan syndrome who also have anomalous aortic origin of a coronary artery. The...

  • Takotsubo cardiomyopathy in association with endogenous and exogenous thyrotoxicosis. Hutchings, D.C.; Adlam, D.; Ferreira, V.; Karamitsos, T.D.; Channon, K.M. // QJM: An International Journal of Medicine;May2011, Vol. 104 Issue 5, p433 

    No abstract available.

  • Genetic disorder or toxoplasma myocarditis: a case report of dilated cardiomyopathy with hypertrabeculation in a young asymptomatic woman. Dobranici, M.; Buzea, A.; Popescu, R.; Chirila, L. // Journal of Medicine & Life;Jan-Mar2012, Vol. 5 Issue 1, p110 

    Isolated noncompaction of the left ventricle (LV) is a rare disorder, classified as a primary genetic cardiomyopathy by the American Heart Association. The European Society of Cardiology Working Group on Myocardial and Pericardial Diseases classified LV noncompaction as an unclassified...

  • Toxoplasmosis or left ventricular hypertrabeculation/non-compaction. Finsterer, J.; Stollberger, C. // Journal of Medicine & Life;Jul-Sep2012, Vol. 5 Issue 3, p258 

    A letter to the editor is presented in response to the article "Genetic disorder or toxoplasma myocarditis: a case report of dilated cardiomyopathy with hypertrabeculation in a young asymptomatic woman," by M. Dobranici and colleagues in the 2012 issue.

  • Tumor Encasement of the Right Coronary Artery: Role of Anatomic and Functional Imaging in Diagnosis and Therapeutic Management. Yu-Hsiang Juan; Chatzizisis, Yiannis S.; Saboo, Sachin S.; Rocha, Tatiana; Steigner, Michael L. // Open Cardiovascular Medicine Journal;2014, Vol. 8, p110 

    We presented two rare cases of mediastinal tumor encasing the right coronary artery (RCA), one with recurrent metastatic thymoma and another with primary poorly differentiated neoplasm. Different degrees and locations of RCA involvement were noted. The treatment approach varied from conservative...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics