Pericardial Effusion in Severe Hypothyroidism in Children

Martinez-Soto, Tania; Deal, Cheri; Stephure, David; Trussell, Rebecca; Boutin, Christine; Djemli, Anissa; Ho, Josephine
November 2010
Journal of Pediatric Endocrinology & Metabolism;Nov2010, Vol. 23 Issue 11, p1165
Academic Journal
The article presents six cases of pleural and pericardial effusion in children with severe hypothyroidism. The methods of identifying the patients are explained through cross-referencing and data collection. The clinical characteristics of each patient are provided, most of whose pericardial effusion occur in association with trisomy 21. Its pathophysiology is discussed involving increasing capillary permeability with leakage of plasma proteins.


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