Common Skeletal Growth Retardation Disorders Resulting from Abnormalities within the Mesenchymal Stem Cells Reservoirs in the Epiphyseal Organs Pertaining to the Long Bones

Bickels, Jacob; Weinstein, Talia; Robinson, Dror; Nevo, Zvi
November 2010
Journal of Pediatric Endocrinology & Metabolism;Nov2010, Vol. 23 Issue 11, p1107
Academic Journal
The article presents information on a study which identified the sites and routes of migration of the reservoirs of the mesenchymal precartilaginous stem cells of the developing limbs and the events that can lead to skeletal growth retardation disorders. The framework of normal limb formation includes those of the cartilage structures and physiological functioning within the limb. The sites of the initial abnormal pathological events of limb development are presented.


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