Solid and Papillary Epithelial Neoplasms of the Pancreas: Aggressive Resection for Cure

Yoon, Diana Y.; Hines, Oscar J.; Reber, Howard A.; Bilchik, Anton J.; Lewin, Klaus; Cortina, Galen
December 2001
American Surgeon;Dec2001, Vol. 67 Issue 12, p1195
Academic Journal
Solid and papillary epithelial neoplasms of the pancreas (SPENP) are extremely rare and usually affect young women. We retrospectively reviewed our experience with pancreatic neoplasms from 1986 to the present and identified nine patients with SPENP. All nine patients were female with a mean age of 32 years (range 16-66). All patients presented with gastrointestinal complaints including pain, mass, dyspepsia, or bloating and were subsequently diagnosed with a tumor of the pancreas by CT scan. All patients underwent surgical resection. Two patients had tumors located in the head of the pancreas and underwent a pancreaticoduodenectomy. The remainder had tumors located in the tail of the pancreas and underwent distal pancreatectomy. Pathology demonstrated solid and papillary or solid and cystic pseudopapillary neoplasm of the pancreas. Three tumors were positive for both vimentin and alpha-1 antitrypsin on immunohistochemical studies, and three were positive for neuron-specific enolase. All nine patients underwent curative resection and are alive without any evidence of recurrence with a mean follow-up of 5.4 years. SPENP is considered to be a low-grade malignancy with an excellent prognosis. Prompt diagnosis and surgical resection can result in cure.


Related Articles

  • Solid pseudopapillary tumor of the pancreas. Govindaraj, Edigara; Ahemad, Nihal; Meti, Ravindranath M. // International Journal of Health & Allied Sciences;Apr-Jun2015, Vol. 4 Issue 2, p103 

    The solid pseudopapillary tumor of the pancreas (SPPT) is an unusual low-grade malignant epithelial tumor affecting predominantly adolescent girls and young women, usually misdiagnosed as pancreatic pseudocyst. Although approximately 500 cases of SPTP have been described in the last 40 years,...

  • An Unusual Clinical Presentation of Pancreatic Solid Pseudopapillary Tumor With Ovarian Metastases: A Diagnostic Dilemma. Mete, Özgür; Yeğen, Gülçin; Güllüoğlu, Mine G.; Kapran, Yersu; Klöppel, Günter // International Journal of Surgical Pathology;Jun2011, Vol. 19 Issue 3, p342 

    The article discusses the clinical case of a 55-year-old female who was diagnosed with pancreatic solid pseudopapillary tumor (SPT) with ovarian metastases. The patient complained of abdominal pain. Magnetic resonance imaging on the patient revealed a metastatic pancreatic tumor with SPT. She...

  • Sclerosing Epithelioid Fibrosarcoma Primary of the Bone. Abdulkader, Ihab; Cameselle-Teijeiro, Jose; Fraga, Maximo; Caparrini, Ana; Forteza, Jeronimo // International Journal of Surgical Pathology;Jul2002, Vol. 10 Issue 3, p227 

    Reports on a case of sclerosing epithelioid fibrosarcoma primary of the left iliac bone. Results of histologic examinations; Morphologic patterns and immunohistochemical profiles; Implications on surgical pathology.

  • Pancreatic endocrine tumours. Carter, D.C. // British Medical Journal (Clinical Research Edition);3/7/1987, Vol. 294 Issue 6572, p593 

    Focuses on the development of pancreatic endocrine tumours. Relation of the cell islet tumours and peptic ulceration; Efficiency of amine precursor uptake and decarboxylation for digestion control and carbohydrate metabolism; Efficacy of cytotoxic treatment.

  • A case of vague abdominal pain. Surawicz, Christina M. // Cortlandt Forum;10/25/96, Vol. 9 Issue 10, p182 

    Details a case where a 58-year-old man was diagnosed with cystic neoplasms of the pancreas. Presenting symptoms; Differential diagnosis for the condition; Incidence of the disease; Differentiation from pseudocysts.

  • Back Cover: Plasma Process. Polym. 3/2019.  // Plasma Processes & Polymers;Mar2019, Vol. 16 Issue 3, pN.PAG 

    Back Cover: The glow‐like helium atmospheric pressure plasma jet is combined with clinical antitumor drug‐ Tegafur‐ to treat pancreatic tumor cells in vitro by employing two kinds of adding sequences (① plasma + drug; ② drug + plasma). The synergistic effect on...

  • Centralising care for patients with pancreatic cancer: a hybrid model approach. Gandy, Robert C.; Haghighi, Koroush // Medical Journal of Australia;1/16/2017, Vol. 206 Issue 1, p21 

    The article presents author's comments on the use of hybrid model for centralising the medical care for patients with pancreatic cancer.

  • At a glance: 25 fibrous tumors of the pancreas. Santos, Vitorino Modesto; santos, Lister Arruda Modesto // Revista de Medicina e Saúde de Brasília;Set-Dec2017, Vol. 6 Issue 3, p430 

    Solitary fibrous tumor of the pancreas is a rare condition, more often benign. Mesenchymal fibroblastic-like spindle cells, anarchical fascicular pattern, hyalinized fibro collagen stroma, and hemangiopericytoma-like vessels are the usual features. Suggestive histopathology data must be...

  • Correction to: Phase Ib/II study of gemcitabine, nab-paclitaxel, and pembrolizumab in metastatic pancreatic adenocarcinoma. Weiss, Glen J.; Blaydorn, Lisa; Beck, Julia; Bornemann-Kolatzki, Kirsten; Urnovitz, Howard; Schütz, Ekkhard; Khemka, Vivek // Investigational New Drugs;Aug2019, Vol. 37 Issue 4, p797 

    The authors would like to note an error in Figures 1 and 2 of this paper. The graph in Figure 1 incorrectly reflected the overall survival (OS), when it should have displayed the progression-free survival (PFS). The caption and median PFS values were correct.

  • Soft-tissue images. Malignant degeneration of heterotopic pancreas.  // Canadian Journal of Surgery;Dec2001, Vol. 44 Issue 6, p407 

    Presents soft-tissue images of malignant degeneration of heterotopic pancreas. Medical history of a 60-year-old male smoker; Diagnosis of adenocarcinoma; Performance of thoracotomy; Description of the surgical specimen; Characteristics of the malignant tumor.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics