TITLE

Physical disease in schizophrenia: a population-based analysis in Spain

AUTHOR(S)
Bouza, Carmen; López-Cuadrado, Teresa; Amate, José María
PUB. DATE
January 2010
SOURCE
BMC Public Health;2010, Vol. 10 Issue 1, p745
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Physical disease remains a challenge in patients with schizophrenia. Our objective was to determine the epidemiological characteristics and burden of physical disease in hospitalized patients with schizophrenia. Methods: We analyzed the 2004 Spanish National Hospital Discharge Registry, identified records coded for schizophrenia (295.xx) and characterized the physical diseases using the ICD-9 system and the Charlson Index. We also calculated standardized mortality ratios (SMRs) versus the general population adjusted by age and calendar time. Results: A total of 16, 776 cases (mean age: 43 years, 65% males) were considered for analysis. Overall, 61% of cases had at least one ICD-9 physical code and 32% had more than one ICD-9 code. The Charlson index indicated that 20% of cases had a physical disease of known clinical impact and prognostic significance. Physical disease appeared early in life (50% of cases were 15-31 years of age) and increased rapidly in incidence with age. Thus, for patients aged 53 years or more, 84% had at least one physical ICD-9 code. Apart from substance abuse and addiction, the most prevalent diseases were endocrine (16%), circulatory (15%), respiratory (15%), injury-poisoning (11%), and digestive (10%). There were gender-related differences in disease burden and type of disease. In-hospital mortality significantly correlated with age, the Charlson Index and several ICD-9 groups of physical disease. Physical disease was associated with an overall 3.6-fold increase in SMRs compared with the general population. Conclusions: This study provides the first nationally representative estimate of the prevalence and characteristics of physical disease in hospitalized patients with schizophrenia in Spain. Our results indicate that schizophrenia is associated with a substantial burden of physical comorbidities; that these comorbidities appear early in life; and that they have a substantial impact on mortality. This information raises concerns about the consequences and causes of physical disorders in patients with schizophrenia. Additionally, it will help to guide the design and implementation of preventive and therapeutic programs from the viewpoint of clinical care and in terms of healthcare service planning.
ACCESSION #
57224031

 

Related Articles

  • Consenso sobre la salud física del paciente con esquizofrenia de las Sociedades Españolas de Psiquiatría y de Psiquiatría Biológica. Ruiz, J. Sáiz; García, J. Bobes; Ruiloba, J. Vallejo; Ubago, J. Giner; González, M. P. García-Portilla // Actas Espanolas de Psiquiatria;sep2008, Vol. 36 Issue 5, p31 

    Introduction. Schizophrenia has traditionally been associated with higher rates of physical comorbidity and excess mortality. Objective. To develop a Spanish consensus document concerning the physical health of patients with schizophrenia and the interventions required to reduce the...

  • Time trends in schizophrenia mortality in Stockholm County, Sweden: cohort study. Osby, Urban; Correia, Nestor; Brandt, Lena; Ekbom, Anders; Sparen, Par // BMJ: British Medical Journal (International Edition);08/19/2000, Vol. 321 Issue 7259, p483 

    Presents a study of mortality rates among Swedish patients with schizophrenia. Categories of causes of death used in the study; Impact of hospital admission on rates of mortality from suicide; Details of the estimation of mortality rates and calculation of mortality ratios; Indications of...

  • Direct costs of schizophrenia in Italian community psychiatric services. Garattini, L.; Rossi, C.; Tediosi, F.; Cornaggia, C.; Covelli, G.; Barbui, C.; Parazzini, F. // PharmacoEconomics;Dec2001, Vol. 19 Issue 12, p1217 

    Objective: To estimate resource utilisation and direct costs of treatment for patients with schizophrenia in Italian Community Mental Health Centers (CMHCs).Design: Multicentre, retrospective observational study. CMHCs recruited all patients who attended a follow-up...

  • POLICY MAKING'S UNINTENDED CONSEQUENCES. Oss, Monica E. // Behavioral Healthcare;Mar2006, Vol. 26 Issue 3, p56 

    Comments on the proposed preauthorization requirements for newer antipsychopathic access to people who suffer from schizophrenia in the Medicaid program in Iowa. Disadvantages of the proposal; Other options that can be considered in managing the cost of the treatment of schizophrenia; Planning...

  • Burden on caregivers of people with schizophrenia: comparison between Germany and Britain. Roick, C.; Heider, D.; Bebbington, P. E.; Angermeyer, M. C.; Azorin, J.-M.; Brugha, T. S.; Kilian, R.; Johnson, S.; Toumi, M.; Kornfeld, Å.; Roick, Christiane; Heider, Dirk; Bebbington, Paul E; Angermeyer, Matthias C; Azorin, Jean-Michel; Brugha, Traolach S; Kilian, Reinhold; Johnson, Sonia; Toumi, Mondher; Kornfeld, Asa // British Journal of Psychiatry;Apr2007, Vol. 190, p333 

    Background: Burden on the relatives of patients with schizophrenia may be influenced not only by patient and caregiver characteristics, but also by differences in mental health service provision.Aims: To analyse whether family burden is affected by national differences...

  • Clinical: The link between diabetes and schizophrenia. Dinan, Ted; Peveler, Robert; Holt, Richard // GP: General Practitioner;9/9/2005, p66 

    The article reports that GPs are best placed to screen schizophrenic patients for other health risks. GPs aware of the increased risks of schizophrenia should attempt to screen patients for impaired glucose tolerance and type-2 diabetes. GPs are the best chance patients with schizophrenia--often...

  • Poor physical health and mortality in patients with schizophrenia. Pack, Steven // Nursing Standard;1/28/2009, Vol. 23 Issue 21, p41 

    Schizophrenia, its treatment and the lifestyle of patients contribute to high rates of mortality. Patients often have poorer diets, lower rates of physical activity and smoke more than the general population. Such lifestyle choices predispose them to physical health problems and disease. This...

  • Five-year mortality in a cohort of people with schizophrenia in Ethiopia.  // BMC Psychiatry;2011, Vol. 11 Issue 1, p165 

    The article focuses on a community-based report on a cohort of people with schizophrenia in Ethiopia. It is concluded that the alarmingly high mortality found in this patient population is of major concern. As stated, most patients died because of potentially treatable conditions. The...

  • An investigation of economic costs of schizophrenia in two areas of China. Jinguo Zhai; Xiaofeng Guo; Min Chen; Jingping Zhao; Zhonghua Su // International Journal of Mental Health Systems;2013, Vol. 7 Issue 1, p1 

    Background Schizophrenia is a severe psychotic disorder characterized by significant disturbances in thinking, perception, emotions and behavior. Even if it is not a very frequent disorder, but it is the most burdensome and costly illnesses worldwide. The total population was approximate 1.3...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics