TITLE

Cervical cancer screening in Australia: modelled evaluation of the impact of changing the recommended interval from two to three years

AUTHOR(S)
Creighton, Prudence; Jie-Bin Lew; Clements, Mark; Smith, Megan; Howard, Kirsten; Dyer, Suzanne; Lord, Sarah; Canfell, Karen
PUB. DATE
January 2010
SOURCE
BMC Public Health;2010, Vol. 10, p734
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The National Cervical Screening Program in Australia currently recommends that sexually active women between the ages of 18-70 years attend routine screening every 2 years. The publically funded National HPV Vaccination Program commenced in 2007, with catch-up in females aged 12-26 years conducted until 2009; and this may prompt consideration of whether the screening interval and other aspects of the organized screening program could be reviewed. The aim of the current evaluation was to assess the epidemiologic outcomes and cost implications of changing the recommended screening interval in Australia to 3 years. Methods: We used a modelling approach to evaluate the effects of moving to a 3-yearly recommended screening interval. We used data from the Victorian Cervical Cytology Registry over the period 1997-2007 to model compliance with routine screening under current practice, and registry data from other countries with 3-yearly recommendations to inform assumptions about future screening behaviour under two alternative systems for screening organisation - retention of a reminder-based system (as in New Zealand), or a move to a call-and-recall system (as in England). Results: A 3-yearly recommendation is predicted to be of similar effectiveness to the current 2-yearly recommendation, resulting in no substantial change to the total number of incident cervical cancer cases or cancer deaths, or to the estimated 0.68% average cumulative lifetime risk of cervical cancer in unvaccinated Australian women. However, a 3-yearly screening policy would be associated with decreases in the annual number of colposcopy and biopsy procedures performed (by 4-10%) and decreases in the number of treatments for preinvasive lesions (by 2-4%). The magnitude of the decrease in the number of diagnostic procedures and treatments would depend on the method of screening organization, with call-and-recall screening associated with the highest reductions. The cost savings are predicted to be of the order of A$10-18 M annually, equivalent to 6-11% of the total cost of the current program (excluding overheads), with call-and-recall being associated with the greatest savings. Conclusions: Lengthening the recommended screening interval to 3 years in Australia is not predicted to result in increases in rates of cervical cancer and is predicted to decrease the number of women undergoing diagnostic and treatment procedures. These findings are consistent with a large body of international evidence showing that screening more frequently than every three years with cervical cytology does not result in substantial gains in screening effectiveness.
ACCESSION #
57223654

 

Related Articles

  • Epidemiology of cervical cancer in Colombia. Muño, Nubia; Eduardo Bravo, Luis // Salud Pública de México;sep/oct2014, Vol. 56 Issue 5, p431 

    Objective. To describe the incidence, mortality, time trends and prognostic factors for cervical cancer in Cali, Colombia, and to review the molecular epidemiological evidence showing that HPV is the major and necessary cause of cervical cancer and the implications of this discovery for primary...

  • Simplified GOG risk criteria validated in stage IB cervical cancers.  // Hem/Onc Today;4/25/2010, Vol. 11 Issue 8, p47 

    The article focuses on a research by Dr. Hee-Sug Ryu of the Ajou University Hospital about the risk criteria of the Gynecologic Oncology Group (GOG) for treatment of patients with stage IB cervical cancers after radical hysterectomy presented at The Society for Gynecologic Oncologists' 2010...

  • Disseminating Cervical Cancer Knowledge: Impact of a Public Seminar. Parhizkar, Saadat; Latiff, Latiffah Abdul; Afshari, Mojgan // International Journal of Learning & Development;2013, Vol. 3 Issue 1, p203 

    Cervical cancer is the second most common cancer after breast cancer among women in Malaysia. Cervical cancer screening using Pap smear provides an appropriate way for early detection and prevention of cervical cancer if appropriately implemented. Knowledge and attitudes toward disease and...

  • Screening for cervical cancer and the associated factors among women in Delhi, India. Nikhat, Sadiya; Anjum, R.; Khayyam, K. U. // Asian Journal of Pharmaceutical & Health Sciences;Oct-Dec2012, Vol. 2 Issue 4, p472 

    Cervical cancer is one the fastest growing preventable malignancies globally. In 2008, there were 72826 deaths from cervical cancer in India in women of all age-groups, and this figure is projected to increase up to 116171 by the year 2025. Several factors contribute to high burden of disease...

  • Detecting Changes in the Cervix with Raman Spectroscopy. Vargis, Elizabeth; Byrd, Teresa; Reese, Jeff; Khabele, Dineo; Al-Hendy, Ayman; Mahadevan-Jansen, Anita // AIP Conference Proceedings;8/6/2010, Vol. 1267 Issue 1, p441 

    The article focuses on the findings of a research work conducted to detect changes in the cervix with Raman spectroscopy.Cervical cancer is the second commonest cancer in women worldwide. Raman spectroscopy was used to identify dysplastic areas of the cervix to provide automated, real-time...

  • Patient and disease characteristics associated with late tumour stage at presentation of cervical cancer in northwestern Tanzania. Mlange, Ramadhani; Matovelo, Dismas; Rambau, Peter; Kidenya, Benson // BMC Women's Health;1/25/2016, Vol. 16 Issue 5, p1 

    Background: About two thirds of patients with cervical cancer in Tanzania present with advanced tumor stage, leading to significant morbidity and mortality. We designed a study to determine the factors associated with the late tumour stage at presentation among patients with...

  • Comment on 'Characteristics and screening history of women diagnosed with cervical cancer aged 20-29'. Herbert, A; Holdsworth, G; Kubba, A A // British Journal of Cancer;12/9/2014, Vol. 111 Issue 12, p2373 

    A letter to the editor is presented in response to the article "Characteristics and screening history of women diagnosed with cervical cancer aged 20?29" in the 2013 issue.

  • Cases of cervical cancer among young women soar. Moberly, Tom // GP: General Practitioner;11/11/2011, p11 

    The article focuses on a study conducted by the cancer research organization Cancer Research UK revealing rise in the percentage of women with cervical cancer in Great Britain. It shows 60 percent increase in the number of women in their 20s with cervical cancer from 1992-2008 and identifies...

  • B7-H4 overexpression correlates with a poor prognosis for cervical cancer patients. WENTING LIU; KIYOSUMI SHIBATA; YOSHIHIRO KOYA; HIROAKI KAJIYAMA; TAKESHI SENGA; MAMORU YAMASHITA; FUMITAKA KIKKAWA // Molecular & Clinical Oncology;2014, Vol. 2 Issue 3, p219 

    Cervical cancer is a major global public health care concern and the second most commonly diagnosed malignancy among females worldwide. B7-H4 is an immunoregulatory protein that has been shown to be overexpressed in several types of cancer and is often associated with more advanced disease and...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics