Photostabilization of Retinol and Retinyl Palmitate by Ethylhexyl Methoxycrylene

Bonda, Craig; Zhang, Jean
January 2011
Cosmetics & Toiletries;Jan2011, Vol. 126 Issue 1, p40
This study examines the photostability of retinol and retinyl palmitate, finding they break down rapidly when exposed to UV radiation in the 290-400 nm range. This severely reduces their concentrations in finished formulations. However, when combined with ethylhexyl methoxycrylene, these retinoids are shown to be protected against photodegradation, thus preserving their concentrations both during the manufacturing process and following application to the skin.


Related Articles

  • Improving the Isotretinoin Photostability by Incorporating in Microemulsion Matrix. Patel, Mrunali R.; Patel, Rashmin B.; Parikh, Jolly R.; Patel, Bharat G. // ISRN Pharmaceutics;2011, Special section p1 

    The present paper demonstrates the increased photostability of isotretinoin when loaded in microemulsion. The photodegradation of isotretinoin, in methanol and microemulsion formulation was studied under direct sun light. The photodegradation process was monitored by UV spectrophotometry. In...

  • UVA/B exposure promotes the biosynthesis of dehydroretinol in cultured human keratinocytes. Tafrova, Juliana; Pinkas-Sarafova, Adriana; Stolarzewicz, Erik; Parker, Kathlyn; Simon, Marcia // Molecular & Cellular Biochemistry;May2012, Vol. 364 Issue 1/2, p351 

    Retinol and its metabolites modulate epithelial differentiation and serve as cellular UV sensors through changes in retinoid status. Of note is the dehydroretinol family which may serve functions distinct from parental retinol. This study focuses on the metabolism of this family and its...

  • Protective Effect of α-Tocopherol-6-O -Phosphate Against Ultraviolet B-Induced Damage in Cultured Mouse Skin. Nakayama, Satomi; Katoh, Eiko M.; Tsuzuki, Toshi; Kobayashi, Shizuko // Journal of Investigative Dermatology;Aug2003, Vol. 121 Issue 2, p406 

    The ability of the novel water-soluble provitamin E, α-tocopherol-6-O -phosphate, to protect against ultraviolet B-induced damage in cultured mouse skin was investigated and compared with the protectiveness of α-tocopherol acetate in cultured mouse skin. Pretreatment of skin with 0.5% (9.4...

  • Seeing spots.  // Dermatology Times;Nov2004, Vol. 25 Issue 11, p85 

    The article reports on the effectiveness of Bright Plus, a new line from Clarins SA that contains vitamin C and raspberry extract, in removing dark splotches caused by ultraviolet radiation. It has been found that spots do not appear completely.

  • UV-Induced Stress and Other Topics. Fox, Charles // Cosmetics & Toiletries;Aug2004, Vol. 119 Issue 8, p0 

    Discusses several skin care studies. Investigation on the skin activation and penetration capability of vitamin E acetate; Use of lignans for prevention or treatment of skin aging; Influence of pre-irradiation on the predictability of in vivo UVA protection.

  • Skin superheroes. Blume, Jillian // Self;Jun2004, Vol. 26 Issue 6, p64 

    Provides information on items that are beneficial to the skin. Vitamins C and E for fighting damage done by the sun's ultraviolet rays; Green tea to improve skin elasticity; Synthetic antioxidant Idebone to slow collagen breakdown and the formation of sunburn cells; Pomegranate's effect against...

  • Skeptic's Corner: Revved-Up Retinol.  // Allure;Jun2012, Vol. 22 Issue 6, p70 

    The article focuses on the need to reduce daily retinol use because it can irritate sensitive skin. It states that Elayda, a company that offers skin care products, mails their customers of a bottle of its transforming complex in increasing retinol's concentrations together with a day cream with...

  • Sun savers. Zavaglia, Mary // Woman's Day (Australia Edition);10/23/2006, Vol. 58 Issue 43, p52 

    The article presents factors to be considered in using and choosing sunscreens such as Sun protection factor (SPF) number, Vitamin E and photostability. Several products, along with their costs and application, are suggested. Sunscreens protect the skin from harmful sun waves such as...

  • LOTION, OR POTION? Pan, Esther // Newsweek (Atlantic Edition);6/10/2002 (Atlantic Edition), Vol. 139 Issue 23, p69 

    Evaluates the product Environ, which claims to restore vitamins to the skin and make skin more resistant to ultraviolet rays. Creation of the product by Des Fernandez in Cape Town, South Africa; Cost of the product, which is high outside of South Africa.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics