Diabetic retinopathy is associated with pulse wave velocity, not with the augmentation index of pulse waveform

Ogawa, Osamu; Hiraoka, Kiyoko; Watanabe, Takahiro; Kinoshita, Junichiro; Kawasumi, Masahiko; Yoshii, Hidenori; Kawamori, Ryuzo
January 2008
Cardiovascular Diabetology;2008, Vol. 7, p1
Academic Journal
Background: To investigate the clinical differences between pulse wave velocity and augmentation index in diabetic retinopathy. Methods: The subjects were 201 patients with type 2 diabetes. These subjects were measured for both augmentation index (AI) and brachial-ankle pulse wave velocity (baPWV) by a pulse wave analyzer. The relationships between AI, baPWV, and diabetic retinopathy were examined. Results: BaPWV was significantly higher in patients with diabetic retinopathy than in individuals without the disease. (20.13 � 3.66 vs.17.14 � 3.60 m/s p < 0.001) AI was higher in patients with diabetic retinopathy, but not significantly. (19.5 � 15.2 vs. 14.8 � 20.5% p = 0.14) The association between baPWV and diabetic retinopathy remained statistically significant after adjustment. (Odds ratio: 1.21 Per m/s, 95% confidence interval: 1.07-1.37) On the other hand, the association between AI and diabetic retinopathy was not statistically significant. (Odds ratio: 1.01 Per %, 95% confidence interval: 0.98-1.03) Conclusion: BaPWV is associated with diabetic retinopathy, but AI is not. The clinical significance appears to be different between PWV and AI in patients with diabetes.


Related Articles

  • Can Self-Rated Health Scores Be Used for Risk Prediction in Patients With Type 2 Diabetes? Hayes, Alison J.; Clarke, Philip M.; Glasziou, Paul G.; Simes, R. John; Drury, Paul L.; Keech, Anthony C. // Diabetes Care;Apr2008, Vol. 31 Issue 4, p795 

    OBJECTIVE -- To investigate whether self-rated health profiles compiled using the EuroQol group's visual analog scale (EQ VAS) are independent predictors of vascular events and major complications in people with type 2 diabetes after controlling for standard clinical risk factors. RESEARCH...

  • Do Patients' Beliefs about Type 2 Diabetes Differ in Accordance with Complications: An Investigation into Diabetic Foot Ulceration and Retinopathy. Searle, Aidan; Wetherell, Mark A.; Campbell, Rona; Dayan, Colin; Weinman, John; Vedhara, Kav // International Journal of Behavioral Medicine;Jul-Sep2008, Vol. 15 Issue 3, p173 

    Background: Previous research has examined patients' beliefs in diabetes and how these beliefs may affect patient outcomes. However, changes in symptoms and complications are a common feature of diabetes, and these can significantly alter the patient's “disease experience.” However,...

  • Switch to insulin affects retinopathy in older diabetic patients.  // Geriatrics;Oct93, Vol. 48 Issue 10, p84 

    Summarizes `Effect of Insulin Therapy on Progression of Retinopathy in Noninsulin-dependent Diabetes Mellitus' by T.K. Roysarker, A. Gupta, R.J. Dash, et al., published in the American Journal of Ophthalmology, 1993, Volume 115: 569-74. Deterioration of retinopathy; Suggestions for metabolic...

  • The Irrefutable Importance of Glycemic Control. Ousman, Yasser; Sharma, Meeta // Clinical Diabetes;Spring2001, Vol. 19 Issue 2, p71 

    Details findings of a prospective observational study designed to determine the relationship between exposure to glycemia over time and the risk of macrovascular and microvascular complications in patients with type 2 diabetes. Primary predefined aggregate clinical outcomes; Incidence of...

  • Tight glycemic control may not be best for all patients with diabetes?  // Endocrine Today;May2009, Vol. 7 Issue 7, p18 

    The article discusses research by Victor M. Montori and Mercè Fernández-Balsells which suggested that tight glycemic control may not reduce the risk for diabetes complications in patients with type 2 diabetes, published in a 2009 issue of "Annals of Internal Medicine."

  • Correction.  // Diabetes Care;Apr2012, Vol. 35 Issue 4, p939 

    A correction to the article "Effect of 3-Month Yoga on Oxidative Stress in Type 2 Diabetes With or Without Complications: A Controlled Clinical Trial," that appeared in the 2011 issue of "Diabetes Care" is presented.

  • Experts call for early, integrated approach to avoid type 2 diabetes complications.  // Endocrine Today;Jun2010 Supplement, Vol. 8, p25 

    The article highlights the findings of a survey on the views of physicians on the need for increased patient understanding of and early, integrated approach to type 2 diabetes complications.

  • Use of Antihypertensive Medications in Patients with type -2 Diabetes in Ajman, UAE. Arifulla, Mohammed; John, Lisha Jenny; Sreedharan, Jayadevan; Muttappallymyalil, Jayakumary; Cheriathu, Jenny; Basha, Sheikh Altaf // Acta Medica Iranica;2015, Vol. 53 Issue 2, p129 

    Optimal reduction in blood pressure with antihypertensive agents helps to prevent microvascular and macro vascular complications of diabetes. The objective of the study was to evaluate the current utilization pattern of antihypertensive medications among patients with diabetes and coexistent...

  • Meta-analysis shows limited benefit of lowering blood pressure below 130/80 mm Hg in patients with type 2 diabetes. Koraishy, Farrukh M.; Peixoto, Aldo J. // Evidence Based Medicine;Dec2013, Vol. 18 Issue 6, p222 

    The authors reflect on the study titled "Intensive and standard blood pressure targets in patients with type 2 diabetes mellitus: systematic review and meta-analysis" by K. McBrien and colleagues published in a 2012 issue of the "Archives of Internal Medicine." Topics include risk of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics