Anal Carcinoma or 'Just Hemorrhoids'?

Winburn, Ginger B.
November 2001
American Surgeon;Nov2001, Vol. 67 Issue 11, p1048
Academic Journal
Cancers of the anal margin and anal canal are extremely rare and often misdiagnosed. Only one to two per cent of large bowel cancers arise in this area. Current management of these cancers includes surgery, combined chemoradiation, or both. From January 1985 through July 2000, 50 patients were diagnosed with anal cancer at two institutions. This retrospective review includes all available cases of anal cancer including all histologies. Patient charts were analyzed for diagnosis, staging, treatment, survival, and recurrence rate. The patients ranged in age from 27 to 92 years (median age 51 years; mean age 52.8 years); there were 22 men and 28 women. The pathologic diagnosis included 44 (88%) with squamous cell carcinoma, three (6%) with melanoma, two (4%) with adenocarcinoma, and one (2%) with Paget's disease. At presentation nine (18%) were classified as stage 0, five (10%) stage I, 21 (42%) stage II, eight (16%) stage III, and seven (14%) stage IV. Mean follow-up data were available on 100 per cent of the patients. Chemoradiotherapy was the primary treatment modality in 25 patients (50%). Ten patients (20%) underwent abdominoperineal resection (APR) in the study. Three patients (6%) received an APR as primary treatment, three (6%) in combination with chemoradiation, and four (8%) for salvage therapy. Fourteen patients (28%) underwent wide local excision (WLE) as the primary treatment. Two patients (4%) underwent WLE plus chemoradiation therapy. One patient (2%) underwent WLE and chemotherapy. There were 18 deaths (36%) in this series. Thirteen patients (26%) died of anal cancer; the average time to death from diagnosis was 13.2 months. Three of these deaths were in patients with melanoma who presented with stage IV disease. Thirty-two patients (64%) are alive, and 30 (60%) of these patients are free of disease (mean time since diagnosis 32.5 months, range 2-151 months). Six patients (12%) had recurrence after treatment (mean time to recurrence 12.6 mont...


Related Articles

  • GA college converts.  // FoodService Director;04/15/98, Vol. 11 Issue 4, p24 

    Reports on cost-cutting goals which were implemented by the Medical College of Georgia, in Augusta, to turn back a move to privatize its foodservice. Percent by which the foodservice budget will be reduced; Renovation of the kitchen for cook-chill.

  • New children's hospital gets parental seal of approval.  // AHA News;10/12/98, Vol. 34 Issue 40, p2 

    Provides information on the children's hospital to be opened at Augusta's Medical College of Georgia. Sponsors of the hospital; Role of parents in designing the hospital; Theme emphasized by hospital organizers.

  • Trends in the incidence of anal cancer in Denmark.  // American Family Physician;8/1/1993, Vol. 48 Issue 2, p328 

    Reports on changes which have occurred since 1960 in the epidemiology of anal cancer in a Denmark. Restriction to epidermoid cancers; Age-adjusted incidence for men and women; Marital history differences for both sexes; Spread of a carcinogenic agent via lifestyle factors.

  • A forty-year experience with anal carcinoma: Changing... Tolmos, Jorge; Vargas, Hernan I. // American Surgeon;Oct1997, Vol. 63 Issue 10, p918 

    Describes the authors' medical experience with anal carcinoma at Harbor-UCLA Medical Center in Torrance, California. System used in the study to stage anal carcinoma; Reasons for the increasing incidence of anal carcinoma among youth; Criticism on the used of radiotherapy as the treatment for...

  • Smear test developed for anal cancer.  // Gastrointestinal Nursing;Nov2008, Vol. 6 Issue 9, p4 

    The article reports on the development of a smear test for anal cancer by the scientists in Cambridge, Massachusetts. The test is based on the fact that normal anal tissue lacks minichromosome maintenance proteins (MCMs). The MCM testing has the ability to detect anal cancer in 235 anal smears...

  • Dessicant cooling reduces peak demand.  // American School & University;Apr94, Vol. 66 Issue 8, p36n 

    Reports on the Medical College of Georgia's use of Semco's desiccant-based cooling system in its Carl T. Sanders Research facility. Function of the system; Benefits of use; Features.

  • Fluoride in black tea may pose health risks.  // Dental Nursing;Aug2010, Vol. 6 Issue 8, p426 

    The article focuses on the study conducted at the Medical College of Georgia in Augusta, Georgia which reveals that drinkers of heavy tea have the risk to bone problems due to high content of fluoride.

  • Desiccant-based cooling system estimated to save medical college $200,000 annually.  // Air Conditioning, Heating & Refrigeration News;2/7/94, Vol. 191 Issue 6, p29 

    Describes the dessicant-based cooling system developed and manufactured by SEMCO Inc. for the Medical College of Georgia. Peak demand and energy consumption reductions; Ability of the system to super dehumidify supply air.

  • Value of clinical pharmacist services applies to ambulatory renal transplant setting, study finds.  // Formulary;Apr2000, Vol. 35 Issue 4, p369 

    Reports on the value of pharmaceutical care activities in a renal transplant clinic at the Medical College of Georgia Hospital & Clinics in Augusta. Staff composition at the clinic; Medications most often involved in accepted recommendations.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics