2010 - Concurrent PPIs and antibiotics for incident C. difficile infection were associated with increased risk for recurrent infection

Fekete, Thomas
October 2010
ACP Journal Club;10/19/2010, Vol. 153 Issue 4, p11
Academic Journal
The article presents the outcomes of a scientific study which aims to find out the risk associated with concurrent prescription of proton pump inhibitors (PPIs) and antibiotics for incident Clostridium difficile infection (CDI). Undertaken by A. Linsky and colleagues it made the use of PPIs based on their clinical effectiveness and perceived safety. It was seen that concurrent prescription for PPI and antibiotics for incident CDI was associated with an increased risk for recurrent CDI.


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