2010 - Prior intensive insulin treatment reduced long-term risk for peripheral neuropathy in type 1 diabetes

Napoli, Mario Di
October 2010
ACP Journal Club;10/19/2010, Vol. 153 Issue 4, p2
Academic Journal
The article presents the outcome of a scientific research which checks the effectiveness of an intensive insulin treatment (IIT) in comparison with conventional treatment for development of peripheral neuropathy in patients with type 1 diabetes. Undertaken by J.W. Albers and colleagues, it was seen that fewer patients in the IIT group had confirmed clinical neuropathy in comparison with conventional treatment. Reduction in peripheral neuropathy was seen in patients who get insulin treatment.


Related Articles

  • Prevalence of Diabetic Peripheral Neuropathy (DPN) and Relation to Glycemic Control Strategies at Baseline in the BARI 2D Cohort. Pop-Busui, Rodica; Lu, Jiang; Lopes, Neuza; Jones, Teresa L. // Diabetes;Jun2007 Supplement 1, Vol. 56, pA79 

    DPN is the most common complication of diabetes (D) and is the leading cause of D-related hospital admissions and nontraumatic amputations, but for which no effective treatment exists. While intensive glycemic control can reduce the incidence of DPN, it is not dear whether the type of glycemic...

  • The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Summary and Future Directions. Gubitosi-Klug, Rose A. // Diabetes Care;Jan2014, Vol. 37 Issue 1, p44 

    OBJECTIVE The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study continues to address knowledge gaps in our understanding of type 1 diabetes and the effects of intensive therapy on its long-term complications. RESEARCH DESIGN AND...

  • Interview with Philip Eaton, M.D., on Creativity in Research. Eldredge, Jonathan // Hypothesis: Journal of the Research Section of MLA;2012, Vol. 24 Issue 1, p15 

    The article presents an interview with clinical researcher Philip Eaton who offered views on two questions on clinical research. Eaton said that an experienced physician detects an exception in a pattern observed in the past hundreds if not thousands of patients with the same presenting problem....

  • New Trends in the Etiopathogenesis of Diabetic Peripheral Neuropathy. Verrotti, Alberto; Giuva, T.; Morgese, G.; Chiarelli, F. // Journal of Child Neurology;Jun2001, Vol. 16 Issue 6, p389 

    Neuropathy is well recognized as a major complication of insulin-dependent diabetes mellitus in adults, resulting in significant morbidity and possibly an increased mortality. Both the peripheral and autonomic nervous systems can be involved, and adolescents with diabetes can show early...

  • Observation on Renal Outcomes in the Veterans Affairs Diabetes Trial. AGRAWAL, LILY; AZAD, NASRIN; EMANUELE, NICHOLAS V.; BAHN, GIDEON D.; KAUFMAN, DERRICK G.; MORITZ, THOMAS E.; DUCKWORTH, WILLIAM C.; ABRAIRA, CARLOS // Diabetes Care;Sep2011, Vol. 34 Issue 9, p2090 

    OBJECTIVE--The Veterans Affairs Diabetes Trial (VADT) was a randomized, prospective, controlled trial of 1,791 patients with type 2 diabetes to determine whether intensive glycemic control would reduce cardiovascular events compared with standard control. The effect of intensive glycemic control...

  • Clinical Diabetic Neuropathy. Bloomgarden, Zachary T. // Diabetes Care;Dec2005, Vol. 28 Issue 12, p2968 

    This article examines the clinical characteristics of diabetic neuropathy in the British Prospective Diabetes Study. It outlines the methodology used in the study. It presents an overview of observational analysis of neuropathy progression. It states the effectiveness of insulin sensitizers in...

  • Dirençli Diyabetik Nöropatik AÄŸrıda Puls Elektromanyetik Alan Tedavisinin EtkinliÄŸi.  // Medical Journal of Trakya University / Trakya Universitesi Tip F;2010, Vol. 27 Issue 3, p227 

    No abstract available.

  • Correlation between neuropathy score and electroneurographic parameters values in patients with painful diabetic polyneuropathy before and after the low intensity laser therapy. Peric, Zoran; Cvetkovic, Bratislav; Stojanovic, Irina; Manic, Gordana // HealthMed;2011, Vol. 5 Issue 4, p711 

    Introduction: Low intensity laser therapy (LILT) is one of methods used in physical medicine for pain reduction in different medical conditions. There are only a few studies about LILT treatment of painful DPN with different results, because pain reduction was not significant in all studies....

  • Astellas Halts Phase II of XenoPort Pain Drug. Young, Donna // BioWorld Today;11/7/2008, Vol. 19 Issue 218, p1 

    The article reports on the announcement by XenoPort Inc. that its Japanese partner Astellas Pharma Inc. terminated a Phase II trial of XP13512, a transported prodrug of gabapentin, in patients with painful diabetic neuropathy (PDN) after an analysis showed it was unlikely the study would reach...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics