TITLE

The incidence of HIV among women recruited during late pregnancy and followed up for six years after childbirth in Zimbabwe

AUTHOR(S)
Munjoma, Marshall W.; Mhlanga, Felix G.; Mapingure, Munyaradzi P.; Kurewa, Edith N.; Mashavave, Grace V.; Chirenje, Mike Z.; Rusakaniko, Simbarashe; Stray-Pedersen, Babill
PUB. DATE
January 2010
SOURCE
BMC Public Health;2010, Vol. 10 Issue 1, p668
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: HIV incidence is a useful tool for improving the targeting of populations for interventions and assessing the effectiveness of prevention strategies. A study in Harare, Zimbabwe reported cumulative incidences of 3.4% (3.0-3.8) and 6.5% (5.7-7.4) among post-partum women followed for 12 and 24 months respectively between 1997 and 2001. According to a Government report on HIV the prevalence of HIV fell from about 30% in 1999 to 14% in 2008. The purpose of this study was to determine the incidence of HIV-1 among women enrolled during late pregnancy and followed for six years after childbirth and to identify risk factors associated with acquisition of HIV. Methods: HIV-uninfected pregnant women around 36 weeks gestation were enrolled from primary health care clinics in peri-urban settlements around Harare and followed-up for up to six years after childbirth. At every visit a questionnaire was interview-administered to obtain socio-demographic data and sexual history since the previous visit. A genital examination was performed followed by the collection of biological samples. Results: Of the 552 HIV-uninfected women 444 (80.4%) were seen at least twice during the six years follow-up and 39 acquired HIV, resulting in an incidence (95% CI) of 2.3/100 woman-years-at-risk (wyar) (1.1-4.1). The incidence over the first nine months post-partum was 5.7/100 wyar (3.3-8.1). A greater proportion of teenagers (15.3%) contributed to a high incidence rate of 2.9/100 (0.6-8.7) wyar. In multivariate analysis lower education of participant, RR 2.1 (1.1-4.3) remained significantly associated with HIV acquisition. Other risk factors associated with acquisition of HIV-1 in univariate analysis were young age at sexual debut, RR 2.3, (1.0-5.6) and having children with different fathers, RR 2.7(1.3-5.8). Women that knew that their partners had other sexual partners were about four times more likely to acquire HIV, RR 3.8 (1.3-11.2). Conclusion: The incidence of HIV was high during the first nine months after childbirth. Time of seroconversion, age and educational level of seroconverter are important factors that must be considered when designing HIV intervention strategies.
ACCESSION #
55564550

 

Related Articles

  • SCHOOL BRIEFS.  // Free Press (Buda, TX);8/6/2008, Vol. 105 Issue 18, p3B 

    The article offers news briefs related to health services in Texas, which include a three-day clinic sponsored by Hays High School's varsity cheer coach Shelley Plumley, services offered by an Austin non-profit agency, and the funding grant received by the Kyle Elementary Environmental Study Center.

  • Opinion: Inside Commissioning - The latest thinking on redesigning healthcare.  // GP: General Practitioner;10/24/2012, p25 

    The article reports on the latest thinking on redesigning healthcare.

  • For the best outcomes, consider patients' culture.  // Patient Education Management;Oct2009, Vol. 16 Issue 10, p116 

    The article discusses the importance of cultural competency to the success of patient care and treatment plan.

  • Integration new normal for Canty. Tophain-Kindley, Liane // New Zealand Doctor;1/30/2013, p13 

    The article reports on the applicability of the concept integrated family health centre, which include the New Zealand healthcare provider Pegasus.

  • Interventional Cardiology.  // Medical Economics;4/3/2009, Vol. 86 Issue 7, p31 

    The article provides information about the development of interventional cardiological centers in the U.S. Intervention centers in the country have become successful in providing cardiology treatments, research development and patient care, as well as recognized as clinical centers of...

  • Recommendations for Management of the Trastuzumab (Herceptin) among Iranian Breast Cancer Patients, a Policy Brief. Rouhollahi, Mohammad Reza; Samad Mohammad Nejad; Harirchi, Iraj; Zarei, Behrouz; Keshtmand, Glavizh; Sedighi, Sanambar; Amanpour, Saeid; Abdirad, Afshin; Kokhaei, Parviz; Aghili, Mehdi; Hashemi, Farnaz Amoozegar; Rajabpour, Mojtaba Vand; Zendehdel, Kazem // Basic & Clinical Cancer Research;May2014, Vol. 6 Issue 2, p27 

    Background: Allocation of the new (expensive) drugs for difficult refractory diseases and financial protection of the patients is an important challenge in the national health systems worldwide especially in developing countries. Trastuzumab (Herceptin) as one of the effective but expensive...

  • New research shows the value of Rx interventions.  // Chain Drug Review;4/18/2016, Vol. 38 Issue 7, p1 

    The article presents a study from American holding company Walgreens Boots Alliance Inc. which reveals the key role of pharmacy interventions in leading to greater medication adherence and lower health care costs.

  • Towards evidence based medicine for paediatricians.  // Archives of Disease in Childhood;Mar2010, Vol. 95 Issue 3, p235 

    The article provides an answer to a question of how to address problems bigger than patient, intervention, comparison and outcome (PICO).

  • Should we use large scale healthcare interventions without clear evidence that benefits outweigh costs and harms? Crump, Bernard // BMJ: British Medical Journal (International Edition);6/7/2008, Vol. 336 Issue 7656, p1276 

    The author reflects on the question of whether physicians should use large health care interventions without evidence that the benefits associated with them outweigh the costs and harm. He suggests that they should and that it does no service to the public to apply yardsticks which were...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics