TITLE

Detection of non-palpable breast cancer in asymptomatic women by using unenhanced diffusion-weighted and T2-weighted MR imaging: comparison with mammography and dynamic contrast-enhanced MR imaging

AUTHOR(S)
Yabuuchi, Hidetake; Matsuo, Yoshio; Sunami, Shunya; Kamitani, Takeshi; Kawanami^1, Satoshi; Setoguchi, Taro; Sakai, Shuji; Hatakenaka, Masamitsu; Kubo, Makoto; Tokunaga, Eriko; Yamamoto, Hidetaka; Honda, Hiroshi
PUB. DATE
January 2011
SOURCE
European Radiology;Jan2011, Vol. 21 Issue 1, p11
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: To compare the detectability of non-palpable breast cancer in asymptomatic women by using mammography (MMG), dynamic contrast-enhanced MR imaging (DCE-MRI) and unenhanced MR imaging with combined diffusion-weighted and T2-weighted images (DWI + T2WI). Methods: Forty-two lesions in 42 patients with non-palpable breast cancer in asymptomatic women were enrolled. For the reading test, we prepared a control including 13 normal and 8 benign cases. Each imaging set included biplane MMG, DCE-MRI and DWI + T2WI. Five readers were asked to rate the images on a scale of 0 to 100 for the likelihood of the presence of cancer and the BI-RADS category. Confidence level results were used to construct receiver operating characteristic analysis. Sensitivity and specificity were calculated for each technique. Results: DWI + T2WI showed higher observer performances (area under the curve, AUC, 0.73) and sensitivity (50%) for the detection of non-palpable breast cancer than MMG alone (AUC 0.64; sensitivity 40%) but lower than those of DCE-MRI (AUC 0.93; sensitivity 86%). A combination of MMG and DWI + T2WI exhibited higher sensitivity (69%) compared with that of MMG alone (40%). Conclusion: DWI + T2WI could be useful in screening breast cancer for patients who cannot receive contrast medium and could be used as a new screening technique for breast cancer.
ACCESSION #
55530725

 

Related Articles

  • Diffusion-weighted imaging (DWI) in MR mammography (MRM): clinical comparison of echo planar imaging (EPI) and half-Fourier single-shot turbo spin echo (HASTE) diffusion techniques. Baltzer, P. A. T.; Renz, D. M.; Herrmann, K.-H.; Dietzel, M.; Krumbein, I.; Gajda, M.; Camara, O.; Reichenbach, J. R.; Kaiser, W. A. // European Radiology;Jul2009, Vol. 19 Issue 7, p1612 

    Diffusion-weighted imaging (DWI) techniques have shown potential to differentiate between benign and malignant neoplasms. However, the diagnostic significance of using DWI under routine conditions remains unclear. This study investigated the use of echo planar imaging (EPI) and half-Fourier...

  • Conspicuity of breast lesions at different b values on diffusion-weighted imaging. Xin Chen; Xi-Jing He; Rui Jin; You-Min Guo; Xian Zhao; Hua-Feng Kang; Li-Ping Mo; Qian We // BMC Cancer;2012, Vol. 12 Issue 1, p334 

    Background: Diffusion-weighted (DW) imaging has shown potential to differentiate between malignant and benign breast lesions. However, different b values have been used with varied sensitivity and specificity. This study aims to prospectively evaluate the influence of b value on the detection...

  • Inter- and intraradiologist variability in the BI-RADS assessment and breast density categories for screening mammograms. REDONDO, A.; COMAS, M.; MACIÀ, F.; FERRER, F.; MURTA-NASCIMENTO, C.; MARISTANY, M. T.; MOLINS, E.; SALA, M.; CASTELLS, X. // British Journal of Radiology;Nov2012, Vol. 85 Issue 1019, p1465 

    Objective: The aim of this study was to evaluate reader variability in screening mammograms according to the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) assessment and breast density categories. Methods: A stratified random sample of 100 mammograms was...

  • Breast cancer screening in the Czech Republic: time trends in performance indicators during the first seven years of the organised programme. Majek, Ondrej; Danes, Jan; Skovajsova, Miroslava; Bartonkova, Helena; Buresova, Lucie; Klimes, Daniel; Brabec, Petr; Kozeny, Pavel; Dusek, Ladislav // BMC Public Health;2011 Supplement 4, Vol. 11 Issue Suppl 4, p288 

    Background: The Czech Breast Cancer Screening Programme (CBCSP) was initiated in September 2002 by establishing a network of accredited centres. The aim of this article is to describe progress in the programme quality over time after the inception of the organised programme. Methods: The CBCSP...

  • Characterization of ductal carcinoma in situ on diffusion weighted breast MRI. Rahbar, Habib; Partridge, Savannah C.; Eby, Peter R.; DeMartini, Wendy B.; Gutierrez, Robert L.; Peacock, Sue; Lehman, Constance D. // European Radiology;Sep2011, Vol. 21 Issue 9, p2011 

    Objectives: To characterize ductal carcinoma in situ (DCIS) and its subtypes on diffusion-weighted imaging (DWI). Methods: We retrospectively reviewed 74 pure DCIS lesions in 69 women who underwent DWI at 1.5 T (b = 0 and 600 s/mm). Each lesion was characterized by qualitative DWI intensity,...

  • Diffusion-weighted MRI in pretreatment prediction of response to neoadjuvant chemotherapy in patients with breast cancer. Richard, Raphael; Thomassin, Isabelle; Chapellier, Marion; Scemama, Aurélie; Cremoux, Patricia; Varna, Mariana; Giacchetti, Sylvie; Espié, Marc; Kerviler, Eric; Bazelaire, Cedric // European Radiology;Sep2013, Vol. 23 Issue 9, p2420 

    Purpose: To evaluate the accuracy of the apparent diffusion coefficient (ADC) provided by diffusion-weighted imaging (DWI) in predicting the response to neoadjuvant chemotherapy (NACT) at baseline in patients according to their breast tumour phenotypes. Materials & methods: This retrospective...

  • Diffusion-Weighted Imaging in 3.0 Tesla Breast MRI: Diagnostic Performance and Tumor Characterization Using Small Subregions vs. Whole Tumor Regions of Interest. Arponent, Otso; Sudah, Mazen; Masarwah, Amro; Taina, Mikko; Rautiainen, Suvi; Könönen, Mervi; Sironen, Reijo; Kosma, Veli-Matti; Sutela, Anna; Hakumäki, Juhana; Vanninen, Ritva // PLoS ONE;10/12/2015, Vol. 10 Issue 10, p1 

    Introduction: Apparent diffusion coefficient (ADC) values are increasingly reported in breast MRI. As there is no standardized method for ADC measurements, we evaluated the effect of the size of region of interest (ROI) to diagnostic utility and correlation to prognostic markers of breast...

  • Breast cancer screening. Newson, Louise // GP: General Practitioner;4/27/2007, p41 

    The article presents information on breast cancer screening. Mammography is currently offered to all women aged 50-70 years to reduce breast cancer mortality in Great Britain. Overdetection of breast cancer may cause harm to a patient. Most women are receiving inadequate information on the...

  • Breast screening `does not save lives'.  // Nature;10/25/2001, Vol. 413 Issue 6858, p764 

    Reports on lack of evidence that the mammography procedure helps detect breast cancer, based on a re-analysis of screening trials by Ole Olsen and Peter Gotzsche of the Nordic Cochrane Center in Copenhagen and the Cochrane Collaboration, an independent body that supports systematic reviews of...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics