TITLE

Pulmonary venous isolation by antral ablation with a large cryoballoon for treatment of paroxysmal and persistent atrial fibrillation: medium-term outcomes and non-randomised comparison with pulmonary venous isolation by radiofrequency ablation

AUTHOR(S)
Kojodjojo, Pipin; O'Neill, Mark D.; Phang Boon Lim; Malcolm-Lawes, Louisa; Whinnett, Zachary I.; Salukhe, Tushar V.; Linton, Nicholas W.; Lefroy, David; Mason, Anthony; Wright, Ian; Peters, Nicholas S.; Kanagaratnam, Prapa; Davies, D. Wyn
PUB. DATE
September 2010
SOURCE
Heart;Sep2010, Vol. 96 Issue 17, p1379
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background To prevent atrial fibrillation (AF) recurrence after catheter ablation, pulmonary venous isolation (PVI) at an antral level is more effective than segmental ostial ablation. Cryoablation around the pulmonary venous (PV) ostia for AF therapy is potentially safer compared to radiofrequency ablation (RFA). The aim of this study was to investigate the efficacy of a strategy using a large cryoablation balloon to perform antral cryoablation with 'touch-up⇔tm) ostial cryoablation for PVI in patients with paroxysmal and persistent AF. Methods Paroxysmal and persistent AF patients undergoing their first left atrial ablation were recruited. After cryoballoon therapy, each PV was assessed for isolation and if necessary, treated with focal ostial cryoablation until PVI was achieved. Follow-up with Holter monitoring was performed. Clinical outcomes of the cryoablation protocol were compared, with consecutive patients undergoing PVI by RFA. Results 124 consecutive patients underwent cryoablation. 77% of paroxysmal and 48% of persistent AF subjects were free from AF at 12 months after a single procedure. Over the same time period, 53 consecutive paroxysmal AF subjects underwent PVI with RFA and at 12 months, 72% were free from AF at 12 months (p=NS). There were too few persistent AF subjects (n=8) undergoing solely PVI by RFA as a comparison group. Procedural and fluoroscopic times during cryoablation were significantly shorter than RFA. Conclusions PV isolation can be achieved in less than 2 h by a simple cryoablation protocol with excellent results after a single intervention, particularly for paroxysmal AF.
ACCESSION #
55416194

 

Related Articles

  • Operation Characteristic of a Heat Pump of Mechanical Vapor Recompression Propelled by Fans and its Performance Analysis Applied to Waste-water Treatment. Pang Weike; Lin Wenju; Pan Qilin; Lin Wenye; Dai Qunte; Yang Luwei; Zhang Zhentao // AIP Conference Proceedings;Jan2014, Vol. 1573, p1122 

    In this paper, a set of heat pump (called as Mechanical Vapor Recompression, MVR) propelled by a centrifugal fan is tested and it shows some special characteristic when it works together with a falling film evaporator. Firstly, an analysis of the fan's suction and discharge parameters at stable...

  • Knowledge, attitude, and behavior in patients with atrial fibrillation undergoing radiofrequency catheter ablation. Wenhua Xu; Guozhen Sun; Zheng Lin; Minglong Chen; Bing Yang; Hongwu Chen; Kejiang Cao // Journal of Interventional Cardiac Electrophysiology;Sep2010, Vol. 28 Issue 3, p199 

    Purpose: Catheter ablation for atrial fibrillation (AF) has become a widely accepted procedure in most of the large cardiac centers throughout the world. However, little is known regarding the knowledge, attitude, and behavior (KAB) of AF patients undergoing radiofrequency catheter ablation...

  • Back on the Right Beat. Hobson, Katherine // U.S. News & World Report;3/13/2006, Vol. 140 Issue 9, p63 

    This article reports on treatments of atrial fibrillation, an irregular heartbeat in the heart's upper chambers. Catheter ablation, the process of putting a catheter into the heart to transmit irregular radio waves to tissue, plus a short course of drug therapy, was found to be more effective...

  • Sustained Fibrillation Within the Left Atrial Appendage During Catheter Ablation for Recurrent Atrial Tachyarrhythmia. Vazquez, Jesus; Biviano, Angelo B.; Garan, Hasan; Whang, William // JAFIB: Journal of Atrial Fibrillation; 

    The left atrial appendage (LAA) has recently been recognized as a potential source of arrhythmia in patients undergoing repeat ablation procedures for atrial fibrillation (AF). In this case report we describe sustained fibrillation contained entirely within the LAA, that continued even after...

  • Combined Catheter Ablation for Atrial Fibrillation and Watchman Left Atrial Appendage Occlusion Procedures: A Single Centre Experience. Walker, Daniel T.; Humphries, Julie A.; Phillips, Karen P. // JAFIB: Journal of Atrial Fibrillation; 

    Background : Patients with atrial fibrillation (AF) may be interested in undergoing concomitant interventions of left atrial catheter ablation and device occlusion of the left atrial appendage (LAA). We report on the feasibility and outcome of combined procedures in a single centre case series...

  • Catheter ablation of atrial fibrillation-patient satisfaction from a single-center UK experience. Ezzat, Vivienne; Chew, Anastasia; McCready, James; Lambiase, Pier; Chow, Anthony; Lowe, Martin; Rowland, Edward; Segal, Oliver // Journal of Interventional Cardiac Electrophysiology;Sep2013, Vol. 37 Issue 3, p291 

    Background: Patient satisfaction is an indicator of quality of care and a key factor for patients' healthcare choices. Although atrial fibrillation (AF) ablation is now common, there are no published data on patient satisfaction during this procedure. Methods: Anonymous patient satisfaction...

  • Safety and Efficacy of Atrial Fibrillation Ablation in Young Patients. Dewire, Jane; Agarwal, Sunil; Khurram, Irfan K.; Marine, Joseph E.; Berger, Ronald; Spragg, David; Ashikaga, Hiroshi; Rickard, John; Nazarian, Saman; Calkins, Hugh // JAFIB: Journal of Atrial Fibrillation;Oct/Nov2013, Vol. 6 Issue 3, p19 

    Background: Outcome of catheter ablation of atrial fibrillation (AF) in young patients has not been widely reported. This study describes the safety and efficacy of radiofrequency catheter ablation (RFA) for atrial fibrillation in patients forty years or younger. Methods and Results: Forty...

  • A nationwide survey on the prevalence of atrioesophageal fistula after left atrial radiofrequency catheter ablation. Kasturi Ghia; Aman Chugh; Eric Good; Frank Pelosi; Krit Jongnarangsin; Frank Bogun; Fred Morady // Journal of Interventional Cardiac Electrophysiology;Jan2009, Vol. 24 Issue 1, p33 

    Abstract Background  There are limited data on the prevalence of atrioesophageal fistula (AEF) after left atrial radiofrequency catheter ablation for atrial fibrillation (AF). The purpose of this study was to determine the prevalence and factors associated with AEF using a nationwide...

  • Bilateral occipital lobe infarction with altitudinal field loss following radiofrequency cardiac catheter ablation. Luu, Susie T.; Lee, Andrew W.; Chen, Celia S. // BMC Cardiovascular Disorders;2010, Vol. 10, p14 

    Background: Bilateral stroke following radiofrequency catheter ablation is an unusual complication and may result in bilateral altitudinal visual field defects. Bilateral altitudinal visual field defects usually result from prechiasmal pathology causing damage to both retinas or optic nerves and...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics