Unethical Guatemalan study may undermine recruitment, trust

December 2010
Clinical Trials Administrator;Dec2010, Vol. 8 Issue 12, p133
The article focuses on the unethical study conducted by U.S. researchers in Guatemala in the 1940s, where soldiers, and mentally ill locals were deliberately infected with syphilis and other sexually-transmitted diseases (STDs) to test the efficacy of antibiotics. It is paralleled with the Tuskegee research in which subjects were not informed of their condition and the intent of the experimentation. Despite the existence of research regulations, it is feared that patient participation in medical tests will be affected.


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