Investigation of Primary Human Immunodeficiency Virus Infection in Patients Who Test Positive for Heterophile Antibody

Walensky, Rochelle P.; Rosenberg, Eric S.; Ferraro, Mary Jane; Losina, Elena; Walker, Bruce D.; Freedberg, Kenneth A.
August 2001
Clinical Infectious Diseases;8/15/2001, Vol. 33 Issue 4, p570
Academic Journal
In light of a recent report of 3 false-positive results of Epstein-Barr virus heterophile tests caused by HIV infection, we sought to assess the frequency of this occurrence. One hundred thirty-two positive heterophile antibody-tested serum samples were obtained from 2 tertiary care facilities in Boston to assess for HIV, and all tested negative for HIV plasma RNA. This study shows that false-positive results of heterophile tests are not frequently associated with primary HIV infection.


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