Acupuncture for functional recovery after stroke: a systematic review of sham-controlled randomized clinical trials

Jae Cheol Kong; Myeong Soo Lee; Byung-Cheul Shin; Yung-Sun Song; Ernst, Edzard
November 2010
CMAJ: Canadian Medical Association Journal;11/9/2010, Vol. 182 Issue 16, p1723
Academic Journal
Background: Acupuncture is frequently advocated as an adjunct treatment during stroke rehabilitation. The aim of this review was to assess its effectiveness in this setting. Methods: We searched 25 databases and 12 major Korean traditional medicine journals from their inception to October 2009. We included randomized controlled trials, with no language restrictions, that compared the effects of acupuncture (with or without electrical stimulation) with sham acupuncture. We assessed the methodologic quality of the trials using the Cochrane risk-of-bias criteria and the PEDro (Physiotherapy Evidence Database) scale. Results: Ten of 664 potentially relevant studies met our inclusion criteria. For acute and subacute stages after stroke, we included seven trials. A meta-analysis of the five studies that assessed functionality did not show a significant difference in favour of acupuncture, with high heterogeneity. A post-hoc sensitivity analysis of three trials with low risk of bias did not show beneficial effects of acupuncture on activities of daily living at the end of the intervention period (n = 244; standard mean difference 0.07, 95% confidence interval [CI] -0.18 to 0.32; I2 = 0%) or after follow-up (n = 244; standard mean difference 0.10, 95% CI -0.15 to 0.35; I2 = 0%). For the chronic stage after stroke, three trials tested effects of acupuncture on function according to the Modified Ashworth Scale; all failed to show favourable effects. Interpretation: Our meta-analyses of data from rigorous randomized sham-controlled trials did not show a positive effect of acupuncture as a treatment for functional recovery after stroke.


Related Articles

  • Acupuncture and stroke rehabilitation. Hongmei Wu // CMAJ: Canadian Medical Association Journal;11/9/2010, Vol. 182 Issue 16, p1711 

    In this article, the author explores the effectiveness of acupuncture in stroke rehabilitation. He tackles the limitations of a study that shows the lack of a positive effect of acupuncture in stroke rehabilitation. He contends that it is premature to refute the influence of acupuncture in the...

  • Randomized Controlled Trials of Acupuncture for Neck Pain: Systematic Review and Meta-Analysis. Li-Min Fu; Ju-Tzu Li; Wen-Shuo Wu // Journal of Alternative & Complementary Medicine;Feb2009, Vol. 15 Issue 2, p133 

    Objectives: The objectives of this study were to assess the effectiveness and efficacy of acupuncture in the treatment of neck pain. Data sources: The following computerized databases were searched from their inception to January 2008: MEDLINE (PubMed), ALT HEALTH WATCH (EBSCO), CINAHL, and...

  • Impact of Including Korean Randomized Controlled Trials in Cochrane Reviews of Acupuncture. Kim, Kun Hyung; Kong, Jae Cheol; Choi, Jun-Yong; Choi, Tae-Young; Shin, Byung-Cheul; McDonald, Steve; Lee, Myeong Soo // PLoS Clinical Trials;Oct2012, Vol. 7 Issue 10, p1 

    Objective: Acupuncture is commonly practiced in Korea and is regularly evaluated in clinical trials. Although many Cochrane reviews of acupuncture include searches of both English and Chinese databases, there is no information on the value of searching Korean databases. This study aimed to...

  • Resources for authors of reports of randomized trials: harnessing the wisdom of authors, editors, and readers. Moher, David; Hopewell, Sally; Schulz, Kenneth F.; Altman, Douglas G. // Trials;2011, Vol. 12 Issue 1, p98 

    The CONSORT Statement was developed to help authors improve the quality of reporting randomized trials. To augment the statement we published the CONSORT explanation and elaboration paper which included at least one example of good reporting for each CONSORT checklist item. We are developing a...

  • Systematic Review of Literature with Different Types of Designs. Manterola, Carlos; Manuel Vial; Pineda, Viviana; Sanhueza, Antonio // International Journal of Morphology;2009, Vol. 27 Issue 4, p1179 

    In certain situations, which occur with particular frequency in the field of surgery and its related disciplines (where what predominates are observational-type studies), the management of randomized controlled clinical trials (RCT) is very difficult and as such, conducting a systematic review...

  • Total Tubeless Versus Standard Percutaneous Nephrolithotomy: A Meta-Analysis. Zhong, Qiang; Zheng, Changjian; Mo, Junfu; Piao, Yongyi; Zhou, Yu; Jiang, Qing // Journal of Endourology;Apr2013, Vol. 27 Issue 4, p420 

    Objective: The aim of this meta-analysis was to evaluate the efficacy and safety of total tubeless percutaneous nephrolithotomy (PCNL) versus standard PCNL. Method: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, and the Chinese Biomedical Literature Database were...

  • Game-Based Digital Interventions for Depression Therapy: A Systematic Review and Meta-Analysis. Li, Jinhui; Theng, Yin-Leng; Foo, Schubert // CyberPsychology, Behavior & Social Networking;Aug2014, Vol. 17 Issue 8, p519 

    The aim of this study was to review the existing literature on game-based digital interventions for depression systematically and examine their effectiveness through a meta-analysis of randomized controlled trials (RCTs). Database searching was conducted using specific search terms and inclusion...

  • Multiple treatment and indirect treatment comparisons: An overview of network meta-analysis. Bhatnagar, Nidhi; Lakshmi, P. V. M.; Jeyashree, Kathiresan // Perspectives in Clinical Research;Oct-Dec2014, Vol. 5 Issue 4, p154 

    Randomized control trials and its meta-analysis has occupied the pinnacle in levels of evidence available for research. However, there were several limitations of these trials. Network meta-analysis (NMA) is a recent tool for evidence-based medicine that draws strength from direct and indirect...

  • A Meta-analysis of Platinum Plus Taxanes Regimen on Treating Advanced Non-small Cell Lung Cancer. Ning ZHU; Jian HE; Siwei ZHANG; Xiaodong CHEN // Chinese Journal of Lung Cancer;Aug2009, Vol. 12 Issue 8, p868 

    Background and objective The platinum-based plus a third-generation agent doublet chemotherapy regimen has been recommended as the standard first-line chemotherapy for advanced NSCLC by ASCO and NCCN. This study was aimed to evaluate the clinical efficacy and side effects of the Platinum plus...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics