A mutational analysis and molecular dynamics simulation of quinolone resistance proteins QnrA1 and QnrC from Proteus mirabilis
- Fluorescence Quenching as a Tool to Investigate Quinolone Antibiotic Interactions with Bacterial Protein OmpF. Neves, Patrícia; Sousa, Isabel; Winterhalter, Mathias; Gameiro, Paula // Journal of Membrane Biology;Feb2009, Vol. 227 Issue 3, p133
The outer membrane porin OmpF is an important protein for the uptake of antibiotics through the outer membrane of gram-negative bacteria; however, the possible binding sites involved in this uptake are still not recognized. Determination, at the molecular level, of the possible sites of...
- Susceptibility of Stenotrophomonas maltophilia to Moxifloxacin, Trovafloxacin, Ofloxacin and Ciprofloxacin. Hawley, H.B.; Polenakovik, H.M.; Czachor, J.S.; Mueller, S.S. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p214
Examines the in vitro susceptibility of clinical isolates of Gram-negative bacterium Stenotrophomonas maltophilia to newer quinolones. Materials and methods; Results.
- Impact of Fluoroquinolone Administration on the Emergence of Fluoroquinolone-Resistant Gram-Negative Bacilli from Grastrointestinal Flora. Richard, Pascale; Delangle, Marie Helene; Raffi, Francois; Espaze, Eric; Richet, Herve // Clinical Infectious Diseases;1/1/2001, Vol. 32 Issue 1, p162
Discusses a study which assessed the risk factors for acquisition of fluoroquinolone-resistant, gram-negative organisms in the gastrointestinal tract of hospitalized patients. Use of fluoroquinolone for the treatment of infections; Methods used; Analysis of risk factors for colonization with...
- Prevalence of Ciprofloxacin Resistance Among Gram-Negative Bacilli at a Specialist Hospital in Saudi Arabia. Ahmad, Shamweel // Bangladesh Journal of Medical Science;Oct2012, Vol. 11 Issue 4, p317
Background: Resistance to antimicrobials of different structural classes including fluoroquinolones has arisen in a multitude of bacterial species both in the community and the hospitals. This may complicate the therapeutic management of infections. Decreased susceptibility to fluoroquinolones...
- The Efficacy of Moxifloxacin-Containing Triple Therapy after Standard Triple, Sequential, or Concomitant Therapy Failure for Helicobacter pylori Eradication in Korea. Kwang Hyun Chung; Dong Ho Lee; Eunhyo Jin; Yuri Cho; Ji Yeon Seo; Nayoung Kim; Sook Hyang Jeong; Jin Wook Kim; Jin-Hyeok Hwang; Cheol Min Shin // Gut & Liver;Nov2014, Vol. 8 Issue 6, p605
Background/Aims: Retreatment after initial treatment failure for Helicobacter pylori is very challenging. The purpose of this study was to evaluate the efficacies of moxifloxacincontaining triple and bismuth-containing quadruple therapy. Methods: A total of 151 patients, who failed initial H....
- Comparative Activity of 7 Quinolones Against Non-Glucose Fermenting Gram-Negative Bacilli Isolated from Cancer Patients. Balakrishnan, M.; Mago, H.; LeBlanc, B.; Rolston, K.V.I. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p190
Evaluates the in vitro activity of seven quinolones against non-glucose fermenting Gram-negative bacilli isolated from clinical specimens of cancer patients. Materials and methods; Results.
- Clinafloxacin Antibacterial Activity. Ednie, L.M.; Jacobs, M.R.; Appelbaum, P.C. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p217
Characterizes the in vitro activity of clinafloxacin compared with other quinolones. Results of MIC testing of several ciprofloxacin-susceptible and -resistant strains; Gram-negative nonfermenters that were generally resistant to quinolones.
- Comparative In Vitro Activity of Grepafloxacin Against Selected Mutants and Clinical Isolates. Soussy, C.J.; Leblanc, F. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p138
Evaluates the in vitro activity of grepafloxacin by agar dilution against quinolone-resistant mutants of Gram-negative bacilli and Enterococcus faecalis and their parent strains. Results; Discussion.
- Effect of Quinolones on Intestinal Ecology. Edlund, C.; Nord, C.E. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p65
Quinolones have a selective effect on the normal human intestinal microflora. Published data on 13 different quinolone agents [ciprofloxacin, enoxacin, norfloxacin, ofloxacin, pefloxacin, lomefloxacin, levofloxacin, sparfloxacin, rufloxacin, sitafloxacin (DU-6859a), gatifloxacin, trovafloxacin...