A mutational analysis and molecular dynamics simulation of quinolone resistance proteins QnrA1 and QnrC from Proteus mirabilis
- Susceptibility of Stenotrophomonas maltophilia to Moxifloxacin, Trovafloxacin, Ofloxacin and Ciprofloxacin. Hawley, H.B.; Polenakovik, H.M.; Czachor, J.S.; Mueller, S.S. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p214
Examines the in vitro susceptibility of clinical isolates of Gram-negative bacterium Stenotrophomonas maltophilia to newer quinolones. Materials and methods; Results.
- Impact of Fluoroquinolone Administration on the Emergence of Fluoroquinolone-Resistant Gram-Negative Bacilli from Grastrointestinal Flora. Richard, Pascale; Delangle, Marie Helene; Raffi, Francois; Espaze, Eric; Richet, Herve // Clinical Infectious Diseases;1/1/2001, Vol. 32 Issue 1, p162
Discusses a study which assessed the risk factors for acquisition of fluoroquinolone-resistant, gram-negative organisms in the gastrointestinal tract of hospitalized patients. Use of fluoroquinolone for the treatment of infections; Methods used; Analysis of risk factors for colonization with...
- Prevalence of Ciprofloxacin Resistance Among Gram-Negative Bacilli at a Specialist Hospital in Saudi Arabia. Ahmad, Shamweel // Bangladesh Journal of Medical Science;Oct2012, Vol. 11 Issue 4, p317
Background: Resistance to antimicrobials of different structural classes including fluoroquinolones has arisen in a multitude of bacterial species both in the community and the hospitals. This may complicate the therapeutic management of infections. Decreased susceptibility to fluoroquinolones...
- The Efficacy of Moxifloxacin-Containing Triple Therapy after Standard Triple, Sequential, or Concomitant Therapy Failure for Helicobacter pylori Eradication in Korea. Kwang Hyun Chung; Dong Ho Lee; Eunhyo Jin; Yuri Cho; Ji Yeon Seo; Nayoung Kim; Sook Hyang Jeong; Jin Wook Kim; Jin-Hyeok Hwang; Cheol Min Shin // Gut & Liver;Nov2014, Vol. 8 Issue 6, p605
Background/Aims: Retreatment after initial treatment failure for Helicobacter pylori is very challenging. The purpose of this study was to evaluate the efficacies of moxifloxacincontaining triple and bismuth-containing quadruple therapy. Methods: A total of 151 patients, who failed initial H....
- Comparative Activity of 7 Quinolones Against Non-Glucose Fermenting Gram-Negative Bacilli Isolated from Cancer Patients. Balakrishnan, M.; Mago, H.; LeBlanc, B.; Rolston, K.V.I. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p190
Evaluates the in vitro activity of seven quinolones against non-glucose fermenting Gram-negative bacilli isolated from clinical specimens of cancer patients. Materials and methods; Results.
- Clinafloxacin Antibacterial Activity. Ednie, L.M.; Jacobs, M.R.; Appelbaum, P.C. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p217
Characterizes the in vitro activity of clinafloxacin compared with other quinolones. Results of MIC testing of several ciprofloxacin-susceptible and -resistant strains; Gram-negative nonfermenters that were generally resistant to quinolones.
- Comparative In Vitro Activity of Grepafloxacin Against Selected Mutants and Clinical Isolates. Soussy, C.J.; Leblanc, F. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p138
Evaluates the in vitro activity of grepafloxacin by agar dilution against quinolone-resistant mutants of Gram-negative bacilli and Enterococcus faecalis and their parent strains. Results; Discussion.
- Effect of Quinolones on Intestinal Ecology. Edlund, C.; Nord, C.E. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p65
Quinolones have a selective effect on the normal human intestinal microflora. Published data on 13 different quinolone agents [ciprofloxacin, enoxacin, norfloxacin, ofloxacin, pefloxacin, lomefloxacin, levofloxacin, sparfloxacin, rufloxacin, sitafloxacin (DU-6859a), gatifloxacin, trovafloxacin...
- Lipopolysaccharide-binding molecules: transporters, blockers and sensors. R. Chaby // Cellular & Molecular Life Sciences;Jul2004, Vol. 61 Issue 14, p1697
Lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria, can be beneficial to the host by activating the innate immune system, or harmful, by inducing inflammation, disseminated intravascular coagulation, multiple organ failure, shock and often death. On the...