Potential new treatments loom for acute leukemia

Thompson, Cheryl A.
November 2010
American Journal of Health-System Pharmacy;11/15/2010, Vol. 67 Issue 22, p1898
Academic Journal
The article reports that two pharmaceutical companies are confident that their lead drug development has the potential in acute myelogenous leukemia (AML) treatment. Cyclacel Pharmaceuticals Inc. says their oral nucleoside analogue, sapacitabine, causes single strand breaks in cancer cell DNA which interferes with the cancer cell mitosis. Meanwhile, Sunesis Pharmaceuticals Inc. mentions that their injectable quinolone derivative, vasaroxin, acts on the enzyme involved in DNA replication.


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