POH02 Impact of chronic vs episodic migraine on disability, health-related quality of life and healthcare resource utilisation in the UK

P J Goadsby
November 2010
Journal of Neurology, Neurosurgery & Psychiatry;Nov2010, Vol. 81 Issue 11, pe51
Academic Journal
OBJECTIVE: Compare impact of chronic migraine (CM) to episodic migraine (EM) on headache-related disability, HRQoL, and healthcare resource utilisation patterns in the UK. METHODS: Cross-sectional data were collected via web-based survey. Respondents were classified as having CM>15 headache days/month or EM<14 headache days/month. Demographic characteristics and healthcare visits within 3 months were assessed. Migraine Disability Assessment Questionnaire and Migraine-specific Quality of Life Questionnaire v2.1 assessed headache-related disability and HRQoL, respectively. Analysis of variance (ANOVA) models predicted HRQoL/disability and logistic regression models examined healthcare resource utilisation by migraine group, adjusting for covariates. RESULTS: Study sample comprises 1070 participants meeting criteria for migraine and providing data on headache frequency: 5% CM (n=57); 95% EM (n=1013). Demographic features were similar in this predominantly female (CM=83%; EM=85%) midlife (mean age 44) sample. CM group reported more severe headache pain (98% vs 82%) than EM, greater headache-related disability, and lower HRQoL. CM sufferers were 3 times (OR 3.1; 95% CI 1.8 to 5.2) as likely to have visited a GP for headache after adjusting for covariates. CONCLUSIONS: CM was associated with greater headache-related-disability, lower HRQoL, and greater healthcare resource utilisation compared to EM supporting the substantial impact of CM on UK sufferers.


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