TITLE

Fluorescein angiography and optical coherence tomography concordance for choroidal neovascularisation in multifocal choroidtis

AUTHOR(S)
Athanasios I Kotsolis
PUB. DATE
November 2010
SOURCE
British Journal of Ophthalmology;Nov2010, Vol. 94 Issue 11, p1506
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
PURPOSE: To compare the utility of fluorescein angiography (FA) and optical coherence tomography (OCT) as diagnostic adjuncts in evaluating symptomatic patients with choroidal neovascularisation (CNV) due to multifocal choroiditis (MFC). METHODS: Patients with CNV due to MFC were retrospectively evaluated in a consecutive fashion. Fundus photography, FA, OCT and biomicroscopy were used to establish the diagnosis. Primary outcome measures included CNV classification (type 1 or occult and type 2 or classic) location and the associated FA and OCT findings. RESULTS: Twenty eyes from 17 patients were included in the study. In 19 eyes (95%) the FA revealed CNV type 2; in one eye (5%) the type of CNV was indeterminate due to a subretinal haemorrhage that covered the lesion. Thirteen eyes had OCT imaging and all revealed hyper-reflectance beneath the neurosensory retina. However, only 53.8% revealed subretinal fluid (SRF) or intraretinal cystic abnormalities. CONCLUSIONS: The CNV in MFC is virtually always type 2, or so-called classic CNV, with vessels beneath the neurosensory retina. Except when blocked by subretinal blood, the neovascularisation is clearly demonstrated by FA. In contrast, only 53.8% of these eyes showed clear evidence of actively proliferating neovascularisation on OCT. Therefore, eyes suspected of having CNV in MFC should be evaluated with FA.
ACCESSION #
54845304

 

Related Articles

  • Optical coherence tomography in progressive cone dystrophy. Zahlava, Jiri; Lestak, Jan; Karel, Ivan // Biomedical Papers of the Medical Faculty of Palacky University i;Dec2014, Vol. 158 Issue 4, p628 

    Aim. The aim of the study was to analyse different clinical pictures in patients with progressive cone dystrophy (PCD), to compare these with the results of optical coherence tomography (OCT) and to evaluate the benefits of this method for diagnosis. Methods. The group consisted of 16 patients...

  • APORTUL TOMOGRAFIEI ÃŽN COERENÅ¢A OPTICÄ‚ ÃŽN DIAGNOSTICUL ÅžI CLASIFICAREA EDEMULUI MACULAR DIABETIC. POPA, DIANA; DEMEA, H.; DEMEA, SORINA; GAVRIS, MONICA // Acta Medica Transilvanica;mar2011, Vol. 16 Issue 1, p37 

    Purpose: is to evaluate the contribution of optical coherence tomography (OCT) in the diagnosis and classification of diabetic macular edema. Material and methods: clinical study of 228 eyes with diabetic macular edema in which OCT was performed. The OCT examination was correlated with...

  • Fluorescein angiography and optical coherence tomography in myopic choroidal neovascularization. Chhablani, J; Deepa, M J; Tyagi, M; Narayanan, R; Kozak, I // Eye;Apr2015, Vol. 29 Issue 4, p519 

    PurposeTo assess intra/inter-observer agreement, and diagnostic capabilities of a color fundus photograph, fundus fluorescein angiography (FFA), and spectral domain optical coherence tomography (SD-OCT) in making a diagnosis of myopic choroidal neovascularization (CNV).Patients and methodsTwo...

  • Ancillary investigations in uveitis. Gupta, Vishali; Gupta, Amod // Indian Journal of Ophthalmology;Jun2013, Vol. 61 Issue 6, p263 

    Ancillary investigations are the backbone of uveitis work-up both for anterior and posterior segment diseases. They help in making the diagnosis, ruling out certain differential diagnosis and monitoring inflammation during the follow-up. This review aims to be an overview describing the role of...

  • Macular edema and visual outcome following cataract surgery in patients with diabetic retinopathy and controls. Eriksson, Urban; Alm, Albert; Bjärnhall, Gunilla; Granstam, Elisabet; Matsson, Anna // Graefe's Archive of Clinical & Experimental Ophthalmology;Mar2011, Vol. 249 Issue 3, p349 

    Background: Cystoid macular edema (CME) is a well-known complication after cataract surgery, and diabetic retinopathy is reported to be an important risk factor for impaired visual recovery. In this prospective study, we compared visual outcome 6 months after surgery in eyes with moderate...

  • Intravitreal ranibizumab for the treatment of choroidal neovascularization secondary to ocular toxoplasmosis. Shah, Nikunj J.; Shah, Urmi N. // Indian Journal of Ophthalmology;Jul2011, Vol. 59 Issue 4, p318 

    The purpose of the study was to report a case of choroidal neovascularization (CNV) secondary to ocular toxoplasmosis in an 18-year-old female patient. She was treated with a single intravitreal injection of ranibizumab. The CNV resolved as confirmed by fluorescein angiography and optical...

  • Bilateral CRAO and CRVO From Thrombotic Thrombocytopenic Purpura: OCT Findings and Treatment With Triamcinolone Acetonide and Bevacizumab. Schwartz, Stephen G.; Hickey, Marcela; Puliafito, Carmen A. // Ophthalmic Surgery, Lasers & Imaging;Sep/Oct2006, Vol. 37 Issue 5, p420 

    A patient with thrombotic thrombocytopenic purpura secondary to adult-onset Still's disease presented with bilateral combined central retinal artery occlusion and central retinal vein occlusion, a rare complication reported only once before. Fundus appearance and fluorescein angiography were...

  • Optical coherence tomography aids in detection and analysis of occult CNV. Hasson, Matt // Ocular Surgery News Europe/Asia-Pacific Edition;Mar2008, Vol. 19 Issue 3, p22 

    The article focuses on the role of optical coherence tomography (OCT) in the diagnosis of occult choroidal neovascularization (CNV). The OCT aids angiography in the diagnosis and detects retinal fluid more effectively according to Gabriel Coscas, and other colleagues in a study published in a...

  • Intravitreal bevacizumab (Avastin) as treatment for subfoveal choroidal neovascularisation secondary to pathological myopia. Yamamoto, Izumi; Rogers, Adam H.; Reichel, Elias; Yates, Paul A.; Duker, Jay S. // British Journal of Ophthalmology;Feb2007, Vol. 91 Issue 2, p157 

    Objective: To evaluate the safety and efficacy of intravitreal bevacizumab (Avastin) as treatment for subfoveal choroidal neovascularisation (CNV) due to pathological myopia. Methods: Consecutive series of primary or recurrent subfoveal CNV secondary to myopia treated with intravitreal...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics