The promise of stem cells
- Stem Cell Research: A Teacher's Primer. Miller, Roxanne Greitz // Delta Kappa Gamma Bulletin;Spring2005, Vol. 71 Issue 3, p17
Written at the novice level of understanding, this article presents to teachers the basic scientific knowledge about stem cells--their use in current and proposed medical therapy, donation of bone marrow or cord blood for use in established stem cell therapy, and the ethical considerations and...
- Blood Stem Cells and non-Hematological Clinical Practice: Pragmatics Before Therapeutics. Parker, Graham C. // Current Pharmaceutical Biotechnology;Feb2007, Vol. 8 Issue 1, p51
There is considerable interest in biological sources for replacement, repair, as well as vascularization of tissue. The remarkable properties of blood stem cells encourage interest in their therapeutic potential. But what are these properties, and how do they influence their clinical potential...
- Human Embryonic Stem Cell Therapies for Neurodegenerative Diseases. Tomaskovic-Crook, Eva; Crook, Jeremy M. // CNS & Neurological Disorders - Drug Targets;Jun2011, Vol. 10 Issue 4, p440
There is a renewed enthusiasm for the clinical translation of human embryonic stem (hES) cells. This is abetted by putative clinically-compliant strategies for hES cell maintenance and directed differentiation, greater understanding of and accessibility to cells through formal cell registries...
- Personalizing Stem Cell Research and Therapy: The Arduous Road Ahead or Missed Opportunity? Patel, S. A.; King, C. C.; Lim, P. K.; Habiba, U.; Dave, M.; Porecha, R.; Rameshwar, P. // Current Pharmacogenomics & Personalized Medicine;2010, Vol. 8 Issue 1, p25
The euphoria of stem cell therapy has diminished, allowing scientists, clinicians and the general public to seriously re-examine how and what types of stem cells would effectively repair damaged tissue, prevent further tissue damage and/or replace lost cells. Importantly, there is a growing...
- Experts warn against "tourist trap" stem cell therapies. Pownall, Mark // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;9/4/2010, Vol. 341 Issue 7771, p477
The article focuses on a warning issued by a group of British specialists on the growing attraction of patients with unproved and potentially dangerous stem cell treatments offered by hundreds of clinics worldwide.
- Stem cell deaths of 3 top pols spark quiz. SALAVERRIA, LEILA B.; UY, JOCELYN R. // Filipino Reporter;6/28/2013, Vol. 41 Issue 30, p1
The article discusses the probe being conducted by the Philippine Medical Association (PMA) regarding the death of three Filipino politicians in March and April 2013 after they separately availed themselves of stem cell therapy using sheep in Germany about six months to a year ago.
- The challenges of stem cell therapy. Di Nardo, Paolo; Singla, Dinender; Ren-Ke Li // Canadian Journal of Physiology & Pharmacology;
The actual repairing power of stem cells has yet to be fully realized because of insufficient knowledge about the basic mechanisms regulating their fate and unsuitable protocols to implant them in injured tissues. Novel strategies must be formulated to fully exploit stem cell potential in the...
- Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. Narsinh, Kazim H.; Sun, Ning; Sanchez-Freire, Veronica; Lee, Andrew S.; Almeida, Patricia; Shijun Hu; Jan, Taha; Wilson, Kitchener D.; Leong, Denise; Rosenberg, Jarrett; Yao, Mylene; Robbins, Robert C.; Wu, Joseph C. // Journal of Clinical Investigation;Mar2011, Vol. 121 Issue 3, p1217
Human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) are promising candidate cell sources for regenerative medicine. However, despite the common ability of hiPSCs and hESCs to differentiate into all 3 germ layers, their functional equivalence at the single cell...
- Corrections. // Nature Medicine;Jul2012, Vol. 18 Issue 7, p995
Corrections to two articles including "The vetting process" that was published in the June 2012 issue and ""Korea okays stem cell therapies despite limited peer-review data" that was published in the March 2012 issue are presented.