Global action urged in response to new breed of drug-resistant bacteria

Webster, Paul Christopher
October 2010
CMAJ: Canadian Medical Association Journal;10/19/2010, Vol. 182 Issue 15, p1602
Academic Journal
The article reports on the warming from a panel of expert micropathologists that urged World Health Organization and all public health agencies to ramp up screening of a drug-resistant bacteria carrying the gene for New Delhi metallo-beta-lactamase-1 (NDM-1). It notes that bacteria became resistant to a board range of beta-lactam antibiotics because of NDM-1. It states that NDM, an enzyme, is widely spread in India because of contaminated water and sewage.


Related Articles

  • Resistance Is Fatal. Allen, Terry J. // In These Times;Jun2011, Vol. 35 Issue 6, p12 

    The article discusses the significance of government funding in safe drinking water, sanitation and healthcare due to the emergence of the New Delhi Metallo-beta-lactamase-1 (NDM-1). It says that the supergene produces an enzyme that provides bacterial resistance to antibiotics. Research...

  • Twelve Positions in a β-Lactamase That Can Expand Its Substrate Spectrum with a Single Amino Acid Substitution. Hyojeong Yi; Kwang-Hwi Cho; Yun Sung Cho; Karan Kim; Nierman, William C.; Heenam Stanley Kim // PLoS ONE;May2012, Vol. 7 Issue 5, p1 

    The continuous evolution of β-lactamases resulting in bacterial resistance to β-lactam antibiotics is a major concern in public health, and yet the underlying molecular basis or the pattern of such evolution is largely unknown. We investigated the mechanics of the substrate fspectrum...

  • Antimicrobial resistance.  // Bulletin of the World Health Organization;Aug2014, Vol. 92 Issue 8, p549 

    The article presents information on an online consultation on a global action plan to address antimicrobial resistance which was launched in July of 2014 by the World Health Organization.

  • An international legal framework to address antimicrobial resistance. Hoffman, Steven J.; Outterson, Kevin; Røttingen, John-Arne; Cars, Otto; Clift, Charles; Rizvi, Zain; Rotberg, Fiona; Tomson, Göran; Zorzet, Anna // Bulletin of the World Health Organization;Feb2015, Vol. 93 Issue 2, p66 

    The article discusses several factors to consider by countries around the world to help solve the problem associated with antimicrobial resistance. Topics noted include areas required for global collective effort such as access, conservation, and innovation, role of international legal framework...

  • More surveillance.  // Drug Topics;7/8/96, Vol. 140 Issue 13, p32 

    Reports that the World Health Organization's Network on Antimicrobial Resistance Monitoring (WHONET) is expanding its efforts into Eastern Africa in cooperation with United States pharmaceutical companies.

  • Effectiveness of 3-Day Amoxycillin vs. 5-Day Co-trimoxazole in the Treatment of Non-severe Pneumonia in Children Aged 2-59 Months of Age: A Multi-centric Open Labeled Trial. Shally Awasthi; Girdhar Agarwal; J. V. Singh; S. K. Kabra; R. M. Pillai; Sunit Singhi; Baridalyne Nongkynrih; Rashmi Dwivedi; Vaishali B. More; Madhuri Kulkarni; A. K. Niswade; Bhavneet Bharti; Ankur Ambast; Puneet Dhasmana; ICMR-IndiaClen Pneumonia Project Group // Journal of Tropical Pediatrics;Dec2008, Vol. 54 Issue 6, p382 

    This cluster randomized, open labeled trial was conducted to compare the effectiveness of 3 days of oral amoxycillin and 5 days of co-trimoxazole treatment in terms of clinical failure in children with World Health Organization (WHO) defined non-severe pneumonia in primary health centers in...

  • β-Lactamase Inhibitors: The Story so Far. Pérez-Llarena, Francisco José; Bou, Germán // Current Medicinal Chemistry;Oct2009, Vol. 16 Issue 28, p3740 

    Antimicrobial resistance constitutes one of the major threats regarding pathogenic microorganisms. Gramnegative pathogens, such as Enterobacteriaceae (specially those producing extended-spectrum β-lactamases), Pseudomonas aeruginosa, and Acinetobacter baumannii, have acquired an important...

  • Arrival of Klebsiella pneumoniae producing KPC carbapenemase in the United Kingdom. Neil Woodford; Jiancheng Zhang; Marina Warner; Mary E. Kaufmann; Jorge Matos; Alan MacDonald; Daniel Brudney; David Sompolinsky; Shiri Navon-Venezia; David M. Livermore // Journal of Antimicrobial Chemotherapy (JAC);Dec2008, Vol. 62 Issue 6, p1261 

    : Background KPC-type carbapenemases are increasingly prevalent in parts of the USA and Israel and are an emerging concern in South America, Europe and China. We investigated the UK’s first two KPC-producing Klebsiella pneumoniae isolates. : Methods The isolates were referred to the...

  • Frecuencia de enzimas asociadas a sensibilidad disminuida a betalactámicos en aislados de enterobacterias, Caracas, Venezuela. Marcano, Daniel; De Jesús, Andreína; Hernández, Luis; Torres, Luis // Revista Panamericana de Salud Publica;Dec2011, Vol. 30 Issue 6, p529 

    Objective. To determine the frequency of enzymatic mechanisms associated with reduced sensitivity to broad-spectrum beta-lactam antibiotics in enterobacteria isolates obtained at hospital centers in Caracas, Venezuela. Methods. A cross-sectional study was conducted on enterobacteria isolated...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics