Blinding: Who, what, when, why, how?

Karanicolas, Paul J.; Farrokhyar, Forough; Bhandari, Mohit
October 2010
Canadian Journal of Surgery;Oct2010, Vol. 53 Issue 5, p345
Academic Journal
The article discusses blinding, a methodology in randomized controlled trials (RCTs) to achieve maximum validity of results. It presents several individuals that should be blinded by trialists, including clinicians, data collectors, and data analysts. It discusses how surgical interventions can apply blinding, in which placebo medications and concealment of scars or incisions can be used to achieve blinding. It notes that if blinding is not possible, allocation groups should be treated equally.


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