Metal Contamination in Biopharmaceutical Drugs

Stellmack, Mary; Rhodes, Kent
October 2010
Contract Pharma;Oct2010, Vol. 12 Issue 8, p84
Trade Publication
The article focuses on the detection of metal contamination in biopharmaceutical drugs. It says that solid and liquid drugs are examined in a microanalysis laboratory with the naked eye first and then through stereomicroscope. It mentions the use of scanning electron microscopy (SEM) and infrared spectroscopy to detect the presence of metal corrosion particles. Furthermore, the wear particles from the processing machinery are the most usual origin of metal contaminants found in pharmaceuticals.


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