Leukodepletion and aprotinin improve clinical outcome after extracorporeal circulation

Gott, John Parker
January 2001
Perfusion;Jan2001 Supplement, Vol. 16 Issue 1S, p5
Academic Journal
Most cardiac operations involve the use of extracorporeal circulation with its attendant systemic inflammatory response syndrome. Many anti-inflammatory strategies hold promise for reducing the associated morbidity of cardiopulmonary bypass. The application of pharmacological and mechanical strategies to control this inflammatory response now has demonstrable clinical benefit. The additional costs of these successful strategies are offset by the economic savings and improved quality of care.


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