TITLE

An update on perfusion safety: does the type of perfusion practice affect the rate of incidents related to cardiopulmonary bypass?

AUTHOR(S)
Stammers, A.H.; Mejak, B.L.
PUB. DATE
May 2001
SOURCE
Perfusion;May2001, Vol. 16 Issue 3, p189
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Cardiopulmonary bypass (CPB) techniques vary among adult and pediatric patients undergoing cardiac surgery. This may result in a differential conduct of CPB between various aged patients. The present study reports on perfusion incidents occurring in hospitals using extracorporeal circulation. An 80 question survey was mailed to chief perfusionists at all 1030 US cardiac surgical centers. Respondents were asked to report on device use and incidents occurring during a 2-year period from July 1996 to June 1998. Five hundred and twenty-four completed surveys were returned with the age of surgical patients operated on at each hospital defined as either an adult (n=407), pediatric (n=17), or combined-adult and pediatric (n=100). Centrifugal pumps were used as the primary systemic pumps in 54% of adult, 12% of pediatric, and 36% of combined centers. In-line blood gas monitoring was used in 76% of all pediatric hospitals, but in only 30% of adult facilities. Incident rates occurred once per every 120.9, 83.9, and 220.2 cases in adult, pediatric, and combined centers, respectively. Mortality rates related to CPB occurred 2.7 times higher in adult and pediatric centers as compared to combined hospitals. Arterial dissection was the number one cause of death in both pediatric and combined hospitals, while coagulation disturbances resulted in the highest mortality for adult procedures. Results of this study show that the lowest incident rates occur at hospitals performing combined adult and pediatric CPB.
ACCESSION #
5437715

 

Related Articles

  • Editorial. Taylor, K. // Perfusion;1999, Vol. 14 Issue 5, p319 

    Editorial. Discusses the introduction of computer control systems into the cardio-pulmonary bypass circuit; Views on mathematical modelling of extracorporeal circulation; Evolution of automated control systems.

  • Vacuum-assisted venous return in pediatric cardiopulmonary bypass. Berryessa, R.; Wiencek, R.; Jacobson, J.; Hollingshead, D.; Farmer, K.; Cahill, G. // Perfusion;Jan2000, Vol. 15 Issue 1, p63 

    Vacuum-assisted venous return (VAVR) has been reported to offer benefits for adults undergoing cardiopulmonary bypass (CPB), such as improved venous return, lowering priming volume (by eliminating the need to prime the venous line), and the use of smaller venous cannulae. All these benefits...

  • Affinity pump system: a new peristaltic blood pump for cardiopulmonary bypass. Jaggy, C.; Lachat, M.; Leskosek, B.; Zünd, G.; Turina, M. // Perfusion;Jan2000, Vol. 15 Issue 1, p77 

    An in vitro study has been carried out to assess the pump performance of a new peristaltic, extracorporeal displacement pump (Affinity) for cardiopulmonary bypass. The pump system consists of a pump rotor (0--110 rpm), a pump chamber, a venous reservoir with a 5/8 connecting tube and the...

  • Heparinless cardiopulmonary bypass with argatroban in dogs Rikitake, Kazuhisa; Okazaki, Yukio; Naito, Kozo; Ohtsubo, Satoshi; Natsuaki, Masafumi; Itoh, Tsuyoshi // European Journal of Cardio-Thoracic Surgery;May2004, Vol. 25 Issue 5, p819 

    Objectives: Systemic heparinization is usually required for cardiopulmonary bypass (CPB). However, problems such as heparin-induced thrombocytopenia, protamine shock, and antithrombin III deficiency exist related to CPB with heparinization. The aim of this study was to evaluate argatroban (ARG)...

  • Phosphodiesterase type 4 inhibitor prevents acute lung injury induced by cardiopulmonary bypass in a rat model Hamamoto, Masaki; Suga, Michiharu; Nakatani, Takeshi; Takahashi, Yuzo; Sato, Yukio; Inamori, Shuji; Yagihara, Toshikatsu; Kitamura, Soichiro // European Journal of Cardio-Thoracic Surgery;May2004, Vol. 25 Issue 5, p833 

    Objectives: Cardiopulmonary bypass (CPB) induces systemic inflammatory response with neutrophil activation and subsequent lung dysfunction. Rolipram, a selective phosphodiesterase type 4 inhibitor, blocks the decrease in levels of cyclic adenosine monophosphate associated with neutrophil...

  • Significant reduction of air microbubbles with the dynamic bubble trap during cardiopulmonary bypass. Schönburg, M.; Urbanek, P.; Erhardt, G.; Kraus, B.; Taborski, U.; Mühling, A.; Hein, S.; Roth, M.; Tiedtke, H.; Klövekorn, W. // Perfusion;Jan2001, Vol. 16 Issue 1, p19 

    Air microbubbles mostly occur unnoticed during cardiopulmonary bypass and are predominantly responsible for serious postoperative psycho-neurological dysfunction. A dynamic bubble trap (DBT), which removes air microbubbles from the arterial blood, was tested in a clinical study. The aim was to...

  • Effects of protective and conventional mechanical ventilation on pulmonary function and systemic cytokine release after cardiopulmonary bypass. Koner, Ozge; Celebi, Serdar; Balci, Huriye; Cetin, Gurkan; Karaoglu, Kamil; Cakar, Nahit // Intensive Care Medicine;Apr2004, Vol. 30 Issue 4, p620 

    Objective: To evaluate the effects of protective and conventional ventilation with or without positive end-expiratory pressure (PEEP), on systemic tumor necrosis factor-alpha, interleukin-6 levels and pulmonary function during open heart surgery.Design: Prospective,...

  • Comparison of the effects of gelatin and a modern hydroxyethyl starch solution on renal function and inflammatory response in elderly cardiac surgery patients. J. Boldt; Ch. Brosch; K. Röhm; M. Papsdorf; A. Mengistu // BJA: The British Journal of Anaesthesia;Apr2008, Vol. 100 Issue 4, p457 

    Background The effects of hydroxyethylstarch (HES) 130/0.4 6% and gelatin 4% on inflammation, endothelial integrity, and renal function after cardiac surgery were compared. Methods Sixty patients aged >80 yr undergoing cardiac surgery were randomized to receive gelatin (n=30) or HES 130/0.4...

  • Conversion to on pump from OPCAB is associated with increased mortality: results from a randomized controlled trial Légaré, Jean-Francois; Buth, Karen J.; Hirsch, Gregory M. // European Journal of Cardio-Thoracic Surgery;Feb2005, Vol. 27 Issue 2, p296 

    Abstract: Objective: Recent developments in cardiac stabilization devices, have made OPCAB feasible. However, there is conflicting evidence to date regarding the rate and adverse events associated with conversion from OPCAB to CABG with CPB. The objective of the present study was to review all...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics