TITLE

Effect of Carmeda® BioActive Surface coating versus Trillium™ Biopassive Surface coating of the oxygenator on circulating platelet count drop during cardiopulmonary bypass

AUTHOR(S)
Palanzo, D.A.; Zarro, D.L.; Manley, N.J.; Montesano, R.M.; Quinn, M.; Elmore, B-A.; Gustafson, P.A.; Castagna, J.M.
PUB. DATE
July 2001
SOURCE
Perfusion;Jul2001, Vol. 16 Issue 4, p279
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
An investigation was conducted to evaluate the effect that surface coating of the hollow-fiber membrane oxygenator had on circulating platelet count drop during cardiopulmonary bypass (CPB). Sixty patients undergoing non-emergency myocardial revascularization for coronary artery disease were randomly divided into two groups. Group one (n=32) received the Carmeda®-coated Maxima-Plus PRF oxygenator while the patients in Group two (n=28) received the Trillium™-coated Affinity oxygenator during CPB. The net platelet count drops for the pump specimen (15–20 min after the initiation of bypass) for the Carmeda and the Trillium groups were 3.6 ± 15.8% and 6.2 ± 10.2%, respectively. The net platelet count drop for the warming specimen for the Carmeda and the Trillium groups were 2.9 ± 19.4% and 0.5 ± 11.0%, respectively. There were no statistically significant differences between the groups. The authors conclude that using either the Carmeda®-coated Maxima-Plus PRF oxygenator or the Trillium™-coated Affinity® oxygenator afford similar benefits in regards to preserving circulating platelet counts during bypass.
ACCESSION #
5437702

 

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