Circuit and protocol for hypoxic hyperthermic isolated limb perfusion to treat malignant melanoma

Innet, L.M.; Haripershad, V.; van den Berg, J.; Cooper, L.
July 2001
Perfusion;Jul2001, Vol. 16 Issue 4, p325
Academic Journal
In the treatment of cancer, isolated limb perfusion (ILP) allows what would be a lethal systemic dose of cytotoxic drugs to be administered directly to a tumour site of an extremity. Unfortunately, ILP is a complex, expensive, time-consuming treatment that requires general anaesthesia, vascular surgery and expertise with extracorporeal circuits that may not be available outside a cardiac centre. By streamlining the traditional ILP protocols and eliminating the oxygenator from the circuit, an equally safe and effective technique of hypoxic hyperthermic isolated limb perfusion has been developed.


Related Articles

  • Zastosowanie wybranych blokad nerwów obwodowych w leczeniu bólu w chorobach nowotworowych. Góraj, Elwira // Palliative Medicine / Medycyna Paliatywna;2012, Issue 3, p111 

    The treatment of cancer pain can involve multiple modalities among them pharmacotherapy and/or interventional techniques. The regional nerve block techniques are an attractive option for poorly controlled by systemic analgesics cancer pain, particularly when is neuropathic in nature. They can...

  • Coeliac plexus block for upper abdominal cancer pain. Chambers, Pauline C. // British Journal of Nursing;7/24/2003, Vol. 12 Issue 14, p838 

    Examines the use of celiac plexus block to relieve intractable pain due to upper abdominal cancer. Percentage of patients reporting significant relief, allowing a reduction in opioid use and the occurrence of opioid-related side effects; Variations in the duration of relief.

  • Accuracy of pulse oximeter perfusion index in thoracic epidural anesthesia under basal general anesthesia. Zifeng Xu; Jianhai Zhang; Yunfei Xia; Xiaoming Deng // International Journal of Clinical & Experimental Medicine;2014, Vol. 7 Issue 7, p1728 

    Objective: To observe the change of PVI after thoracic epidural block on the basis of general anesthesia. Methods: In 26 patients undergoing elective upper abdominal operations, changes of SVI, PVI, SVV, PPV and CVP were monitored immediately before and 10 minutes after T8-9 thoracic epidural...

  • Ultrasound-guided regional anesthesia for ambulatory surgery. Rosenblatt, Meg A. // Revista Mexicana de Anestesiologia;abr-jun2013 supplement, Vol. 36, pS43 

    The article presents details of an ultrasound-guided regional anesthesia for ambulatory surgery. It highlights the advantages of ultrasound-guided regional anesthesia in ambulatory practice. It suggests techniques for learning auxilllary blocks and shows the positive outcomes and effects of...

  • Erfolgreiche Infektionskontrolle bei Regionalanästhesieverfahren. Reisig, F.; Neuburger, M.; Zausig, Y.A.; Graf, B.M.; Büttner, J. // Anaesthesist;Feb2013, Vol. 62 Issue 2, p105 

    Backround: In the context of regional anesthesia procedures adverse events rarely occur but are predominantly systemic intoxication due to local anesthetics (0.01-0.035 %), nerve injuries (0.01-1.7 %) and infections (0-3.2 %). Materials and methods: In a level 1 trauma centre data from all...

  • Dosis de prueba para anestesia regional. Galindo Gualdrón, Luz Adriana // Colombian Journal of Anesthesiology / Revista Colombiana de Anes;Mar2014, Vol. 42 Issue 1, p47 

    Introduction: The use of the test dose in regional anesthesia is not standardized, and there is no consensus regarding what dose it should be or about the anesthetic or type of drug to be used. Moreover, many anesthesiologists do not use it routinely in their practice. Objective: To review the...

  • Analgesic effectiveness of ropivacaine 0.2% vs 0.4% via an ultrasound-guided C5–6 root/superior trunk perineural ambulatory catheter. Fredrickson, M. J.; Price, D. J. // BJA: The British Journal of Anaesthesia;Sep2009, Vol. 103 Issue 3, p434 

    Background: In this prospective, randomized, triple-blinded study, we tested the hypothesis that a 48 h continuous C5–6 root/superior trunk patient-controlled infusion of ropivacaine 0.4% would provide superior analgesia after shoulder surgery compared with the same infusion of...

  • Ultrasound visibility of regional anesthesia catheters: an in vitro study. Takatani, Junji; Takeshima, Naozumi; Okuda, Kentaro; Uchino, Tetsuya; Noguchi, Takayuki // Korean Journal of Anesthesiology;Jul2012, Vol. 63 Issue 1, p59 

    Background: Ultrasound subjective visibility of in-plane needles is correlated with the intensity difference between the needle surface and the background. Regional anesthesia catheters are difficult to visualize by an ultrasound. In the present study, we investigated the ultrasound visibility...

  • Breakage of an Epidural Catheter Inserted for Labor Analgesia. Üşar, Pınar; Kar, Aysun Afife; Çıtak, Güven; Maral, Jale; Canlı, Şeyda // Turkish Journal of Anesthesia & Reanimation;2015, Vol. 43 Issue 4, p282 

    The breakage of an epidural catheter, which is usually not noticed, is a rare but important complication encountered while inserting or removing the catheter during epidural blockade. While the epidural catheter was being inserted for labor analgesia, despite no problem being encountered in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics