An overview of infantile hypertrophic pyloric stenosis

Askew, Nathan
October 2010
Paediatric Nursing;Oct2010, Vol. 22 Issue 8, p27
Academic Journal
HYPERTROPHIC PYLORIC stenosis (HPS) was first described in post-mortem reports in 1717 but was not established as a clinical diagnosis until 1888 when Hirschsprung successfully described two cases (Dudgeon 2005). Initial management of HPS involved medication and feeding, but a high mortality rate resulted. The first surgical treatment of the disease was by Lobker in 1898, however the child died several days later from sepsis (Dudgeon 2005). In 1911, Ramstedt first introduced the pyloromyotomy technique, which is essentially still used, but with a reduced mortality rate of less than 0.4 per cent (Dudgeon 2005). Although significant medical advances have improved the diagnosis, treatment and prognosis of HP S (Panteli 2009), the cause of this disease process remains poorly understood (Dudgeon 2005, Panteli 2009). This article reviews the current literature on the pathophysiology and management of HP S in clinical practice.


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