2010 - Concomitant use of warfarin and cotrimoxazole or ciprofloxacin increased risk for admission for upper GI hemorrhage

Gurwitz, Jerry H.
September 2010
ACP Journal Club;9/21/2010, Vol. 153 Issue 3, p12
Academic Journal
The article presents a study tracing the association between continuous use of antibiotics and upper gastrointestinal tract (UGI) hemorrhage.The study implemented population based, nested case control method, establishing regular use of warfarin and oral cotrimoxazole or ciprofloxacin among older people, resulted in increased risk for UGI hemorrhage. A chart depicting the relation between use of antibiotic warfarin and hospitalization cases for UGI hemorrhage is also presented.


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