2010 - Meta-analysis: Alteplase improves functional outcomes when given within 4.5 hours of stroke onset

Graham, Glenn D.
September 2010
ACP Journal Club;9/21/2010, Vol. 153 Issue 3, p1
Academic Journal
The article presents a study establishing the relation between time and outcomes to the treatment with intravenous Alteplase in acute stroke. According to the randomized controlled trials (RCTs) by K. R. Lees and colleagues, Alteplase improves functional outcomes when given within 4.5 hours of stroke onset. A chart presenting comparison between Ateplase and placebo, in the treatment of acute stroke is also presented.


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