Trends in HIV & syphilis prevalence and correlates of HIV infection: results from cross-sectional surveys among women attending ante-natal clinics in Northern Tanzania

Kumogola, Yusufu; Slaymaker, Emma; Zaba, Basia; Mngara, Julius; Isingo, Raphael; Changalucha, John; Mwidunda, Patrick; Kimaro, Daniel; Urassa, Mark
January 2010
BMC Public Health;2010, Vol. 10 Issue 1, p553
Academic Journal
Background: Sentinel surveillance for HIV in ante-natal clinics (ANC) remains the primary method for collecting timely trend data on HIV prevalence in most of sub-Saharan Africa. We describe prevalence of HIV and syphilis infection and trends over time in HIV prevalence among women attending ante-natal clinics (ANC) in Magu district and Mwanza city, part of Mwanza region in Northern Tanzania. HIV prevalence from ANC surveys in 2000 and 2002 was 10.5% and 10.8% respectively. In previous rounds urban residence, residential mobility, the length of time sexually active before marriage, time since marriage and age of the partner were associated with HIV infection. Methods: A third round of HIV sentinel surveillance was conducted at ante-natal clinics in Mwanza region, Tanzania during 2006. We interviewed women attending 27 ante-natal clinics. In 15 clinics we also anonymously tested women for syphilis and HIV infection and linked these results to the questionnaire data. Results: HIV prevalence was 7.6% overall in 2006 and 7.4% at the 11 clinics used in previous rounds. Geographical variations in HIV prevalence, apparent in previous rounds, have largely disappeared but syphilis prevalence is still higher in rural clinics. HIV prevalence has declined in urban clinics and is stable in rural clinics. The correlates of HIV infection have changed over time. In this round older age, lower gravidity, remarriage, duration of marriage, sexual activity before marriage, long interval between last birth and pregnancy and child death were all associated with infection. Conclusions: HIV prevalence trends concur with results from a community-based cohort in the region. Correlates of HIV infection have also changed and more proximate, individual level factors are now more important, in line with the changing epidemiology of infection in this population.


Related Articles

  • CDC Issues Treatment Guidelines for Nonoccupational HIV Exposure.  // Clinical Infectious Diseases;3/15/2005, Vol. 40 Issue 6, preceding p1 

    The article reports that the U.S. Centers for Disease Control and Prevention have issued guidelines for the use of antiretroviral drugs to prevent HIV infection after non-occupational exposure through sexual intercourse, sexual assault, injection drug use, or accidents. The guidelines recommend...

  • Prevention of AIDS and HIV Infection: Needs and Priorities for Epidemiologic Research. Allen, James R.; Curran, James W. // American Journal of Public Health;Apr88, Vol. 78 Issue 4, p381 

    By the end of 1987, almost 50,000 cases of acquired immunodeficiency syndrome (AIDS) will have been reported in the United States. Although the primary epidemiology of the disease has been described, much work remains to be done to complete our understanding of the dynamics of transmission and...

  • AIDS Drug Assistance Programs in the Era of Routine HIV Testing. Bassett, Ingrid V.; Farel, Claire; Szmuilowicz, Emily D.; Walensky, Rochelle P. // Clinical Infectious Diseases;9/1/2008, Vol. 47 Issue 5, p695 

    AIDS [Acquired Immunodeficiency Syndrome] Drug Assistance Programs, operating within the larger Ryan White Program, are state-based, discretionary programs that provide a drug "safety net" for low-income and uninsured individuals infected with human immunodeficiency virus (HIV). Although the...

  • The Challenge of AIDS-Related Malignancies in Sub-Saharan Africa. Sasco, Annie J.; Jaquet, Antoine; Boidin, Emilie; Ekouevi, Didier K.; Thouillot, Fabian; LeMabec, Thomas; Forstin, Marie-Anna; Renaudier, Philippe; N'Dom, Paul; Malvy, Denis; Dabis, Fran├žois // PLoS ONE;2010, Vol. 5 Issue 1, p1 

    Background: With the lengthening of life expectancy among HIV-positive subjects related to the use of highly active antiretroviral treatments, an increased risk of cancer has been described in industrialized countries. The question is to determine what occurs now and will happen in the future in...

  • FDA Approves New HIV Integrase Inhibitor, Merck Says.  // Clinical Infectious Diseases;12/15/2007, Vol. 45 Issue 12, piv 

    The article reports that a new treatment for HIV infection called Raltegravir made by Merck & Co. Inc. has been approved by U.S. Food and Drug Administration. This is the first integrase inhibitor aimed at preventing replication of the virus. This will be sold under the trade name Isentress. Dr....

  • HIV Infection Presenting in Older Children and Adolescents: A Case Series from Harare, Zimbabwe. Ferrand, Rashida A.; Luethy, Ruedi; Bwakura, Filda; Mujuru, Hilda; Miller, Robert F.; Corbett, Elizabeth L. // Clinical Infectious Diseases;3/15/2007, Vol. 44 Issue 6, p874 

    Background. Symptomatic human immunodeficiency virus (HIV) infection during late childhood and adolescence may be an emerging problem in southern Africa, but it is one that is poorly described. We investigated social and clinical features in patients of this age group presenting to a HIV...

  • Sociodemographic context of the AIDS epidemic in a rural area in Tanzania with a focus on people's mobility and marriage. J T Boerma // Sexually Transmitted Infections;Apr2002, Vol. 78 Issue 0, pi97 

    This analysis focuses on how sociocultural and economic characteristics of a poor semi-urban and rural population (Kisesa ward) in north west Tanzania may directly and indirectly affect the epidemiology of HIV and other sexually transmitted infections (STI). Poverty and sociocultural changes may...

  • Safe versus dangerous germs. Bailey, Janet // Glamour;Sep95, Vol. 93 Issue 9, p62 

    Reports on people's views about contagion. Study of men and women on classification of germs; Threatening depiction of germs from a disliked person, a stranger and romantic partner; Fear of catching a disease from other groups; Lack of concern about risk of getting AIDS from someone known to...

  • Factors predictive of maternal-fetal transmission of HIV-1. Boyer, Pamela J.; Dillon, Maryanne // JAMA: Journal of the American Medical Association;6/22/94-6/29/94, Vol. 271 Issue 24, p1925 

    Assesses maternal risk factors potentially influencing vertical transmission of human immunodeficiency virus, type 1 (HIV-1). Maternal CD4 cell count; Presence of immune complex dissociated (ICD) p24 antigen; Maternal zidovudine therapy during pregnancy and/or delivery; Complications of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics