TITLE

Pulmonary Alveolar Proteinosis in a 67-Year-Old Woman with Wegener’s Granulomatosis

AUTHOR(S)
Shah, Shiwan; Phan, Nghi; Goyal, Geetinder; Sharma, Gulshan
PUB. DATE
October 2010
SOURCE
JGIM: Journal of General Internal Medicine;Oct2010, Vol. 25 Issue 10, p1105
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Mycophenolate mofetil (MM) is commonly used in patients with autoimmune diseases or who have undergone transplantation. Common side effects of MM include anemia, leukopenia, mucositis and opportunistic infections. We report an unusual case of pulmonary alveolar proteinosis (PAP) in a 67-year-old woman on MM for Wegener’s granulomatosis (WG). PAP is a disease characterized by defects in macrophage-mediated processing of surfactants, leading to accumulation of periodic acid-Schiff (PAS)-positive lipoproteinaceous material within the alveolar spaces.
ACCESSION #
53780622

 

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