DNA Sequence Requirements for the Activation of 434 P[sub RM] Transcription by 434 Repressor
- Functional Characterization of Single-Nucleotide Polymorphisms in the Human Undifferentiated Embryonic-Cell Transcription Factor 1 Gene. Thummer, Rajkumar P.; Drenth-Diephuis, Loes J.; Carney, Karen E.; Eggen, Bart J. L. // DNA & Cell Biology;May2010, Vol. 29 Issue 5, p241
Single-nucleotide polymorphisms (SNPs) are single-nucleotide sequence variations between individuals. Two missense SNPs are present in the human undifferentiated embryonic-cell transcription factor 1 ( UTF1) gene and their consequences for UTF1 function are investigated in this study. Expression...
- Tandem binding in crystals of a trp repressor/operator half-site complex. Lawson, Catherine L.; Carey, Jannette // Nature;11/11/1993, Vol. 366 Issue 6451, p178
Presents a tandem complex model which accounts for the mutational sensitivity of all trp operator base pairs. Water-mediated sequence recognition by trp repressor; Role of tandem interactions for amino-terminal arms.
- CREM activator and repressor isoforms in human testis: sequence variations and inaccurate splicing during impaired spermatogenesis. Behr, R.; Weinbauer, G.F. // MHR: Basic Science of Reproductive Medicine;Nov2000, Vol. 6 Issue 11
Examines cAMP responsive element modulator (CREM) transcripts in human testis with normal and impaired spermatogenesis. Identification of activator transcripts; Isolation of CREM repressors from specimens with complete spermatogenesis; Evidence suggesting the presence of several CREM repressor...
- The CK2 Kinase Stabilizes CLOCK and Represses Its Activity in the Drosophila Circadian Oscillator. Szabó, Áron; Papin, Christian; Zorn, Daniela; Ponien, Prishila; Weber, Frank; Raabe, Thomas; Rouyer, François // PLoS Biology;Aug2103, Vol. 11 Issue 8, p1
The CK2 kinase plays diverse roles in the Drosophila circadian clock by controlling stability of the CLOCK transcription factor itself, besides its known role in degrading CLOCK repressors.
- High-throughput SELEX?SAGE method for quantitative modeling of transcription-factor binding sites. Roulet, Emmanuelle; Busso, Stéphane; Camargo, Anamaria A.; Simpson, Andrew J.G.; Mermod, Nicolas; Bucher, Philipp // Nature Biotechnology;Aug2002, Vol. 20 Issue 8, p831
The ability to determine the location and relative strength of all transcription-factor binding sites in a genome is important both for a comprehensive understanding of gene regulation and for effective promoter engineering in biotechnological applications. Here we present a bioinformatically...
- Corrigendum: Real sequence effects on the search dynamics of transcription factors on DNA. Bauer, Maximilian; Rasmussen, Emil S.; Lomholt, Michael A.; Metzler, Ralf // Scientific Reports;8/28/2015, p13045
A correction to the article "Real sequence effects on the search dynamics of transcription factors on DNA" that was published in the previous issue is presented.
- Structural and Functional Analysis of Rice Catalase-B Gene Promoter: Presence of Dof and CAAT Binding Site. Mondal, P.; Dey, N.; Dash, A. K.; Chatterjee, A.; Sahu, B. B.; Panda, B.; Maiti, I. B.; Sabat, S. C. // Plant Molecular Biology Reporter;Jun2007, Vol. 25 Issue 1/2, p71
A 5' flaking nucleotide sequence of 1,101 bp of rice catalase-B gene (CatB) coding sequence having coordinates from -808 to +294 with respect to the transcription start site was transcriptionally fused to the ï¿½-glucuronidase gene (GUS), and functionally analyzed through transient and stable...
- Duplication of the Asymmetric Leaves1/ Rough Sheath 2/Phantastica ( ARP) gene precedes the explosive radiation of the Ruschioideae. Illing, Nicola; Klak, Cornelia; Johnson, Cheryl; Brito, Denise; Negrao, Nuria; Baine, Fiona; van Kets, Victoria; Ramchurn, Kayshinee Rye; Seoighe, Cathal; Roden, Laura // Development Genes & Evolution;Jun2009, Vol. 219 Issue 6, p331
The Mesembryanthemoideae and Ruschioideae subfamilies are a major component of the Greater Cape Floristic Region in southern Africa. The Ruschioideae show an astonishing diversity of leaf shape and growth forms. Although 1,585 species are recognised within the morphologically diverse...
- Novel sequence-based method for identifying transcription factor binding sites in prokaryotic genomes. Sahota, Gurmukh; Stormo, Gary D. // Bioinformatics;Nov2010, Vol. 26 Issue 21, p2672
Motivation: Computational techniques for microbial genomic sequence analysis are becoming increasingly important. With next-generation sequencing technology and the human microbiome project underway, current sequencing capacity is significantly greater than the speed at which organisms of...