Characterization of a Basic Helixï¿½Loop-Helix Protein, ABF-1: Nuclear Localization, Transcriptional Properties, and Interaction with Id-2
- CELL FATE: Making up your mind. Wood, Heather // Nature Reviews Neuroscience;Apr2001, Vol. 2 Issue 4, p225
Discusses a research on the role of neuronal basic helix-loop-helix (bHLH) genes in controlling glial fate decision in cortical progenitors. Reference to a study by M. Nieto et al., published in a 2001 issue of the journal "Neuron"; Mechanism of action of bHLH; Indication of the research findings.
- The basic helix-loop-helix transcription factor family in Bombyx mori. Yong Wang; Keping Chen; Qin Yao; Wenbing Wang; Zhi Zhu // Development Genes & Evolution;Oct2007, Vol. 217 Issue 10, p715
The basic helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that play important roles in a wide range of developmental processes in higher organisms. bHLH family members have been identified in a dozen of organisms including fruit fly, mouse and human. We identified 52...
- Binding of phytochrome B to its nuclear signalling partner PIF3 is reversibly induced by light. Min Ni; Tepperman, James M.; Quail, Peter H. // Nature;8/19/1999, Vol. 400 Issue 6746, p781
Presents research where a nuclear basic helix-loop-helix protein, PIF3 was cloned. How the protein can bind to non-photoactive carboxy-terminal fragments of phytochromes A and B; Conclusions made from results.
- A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex. Kodandapani, Ramadurgam; Pio, Frederic // Nature;4/4/1996, Vol. 380 Issue 6573, p456
Presents a report which specifies the crystal structure of an ETS domain complexed with DNA. The Ets family of transcription factors; Detailed look at the protein-DNA contacts in the PU.1 complex; A call for future extensive mutational studies of amino acids that contact DNA in Ets proteins in...
- Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2. McDowell, Gary S.; Hindley, Christopher J.; Lippens, Guy; Landrieu, Isabelle; Philpott, Anna // BMC Biochemistry;2014, Vol. 15 Issue 1, p2
Background Neuronal differentiation is largely under the control of basic Helix-Loop-Helix (bHLH) proneural transcription factors that play key roles during development of the embryonic nervous system. In addition to well-characterised regulation of their expression, increasing evidence is...
- MXI1. // Encyclopedic Reference of Cancer;2001, p610
An encyclopedia entry for MAX-interacting protein 1 (MXI1) is presented. It refers to a nuclear protein that associates with MAX. It is a ubiquitiously expressed protein (228 aa and 26kD) member of the basic helix-loop-helix family of transcription factors. MXII dimers bind to CAC GTG. It...
- Myogenic Factor 3. // Encyclopedic Reference of Cancer;2001, p614
An encyclopedia entry for myogenic factor 3 is presented. It refers to a nuclear protein (319 aa, 34 kD) involved in muscle differentiation. It induces fibroblasts to differentiate into myoblasts, activating muscle-specific promoters. It belongs to the basic helix-loop-helix family of...
- Characterization of a Novel Class II bHLH Transcription Factor from the Black Widow Spider,, with Silk-Gland Restricted Patterns of Expression. Kohler, Kristin; Thayer, William; Trang Le; Sembhi, Amardeep; Vasanthavada, Keshav; Moore, Anne M. F.; Vierra, Craig A. // DNA & Cell Biology;Jun2005, Vol. 24 Issue 6, p371
Members of the basic helix-loop-helix (bHLH) family are required for a number of different developmental pathways, including lymphopoiesis, myogenesis, neurogenesis, and sex determination. Screening a cDNA library prepared from silk-producing glands of the black widow spider, we have identified...
- New Structural Motifs Isohelical to DNA. Nikitin, A. M.; Gursky, G. V. // Doklady Biochemistry & Biophysics;May/Jun2003, Vol. 390 Issue 1-6, p139
Focuses on several structural motifs that are isohelical to DNA. Function of a structural motif; System used to search for polymeric structures that are isohelical to DNA; Characteristics of the motifs.