TITLE

Prediction of postoperative visual outcome after pars plana vitrectomy based on preoperative multifocal electroretinography in eyes with diabetic macular edema

AUTHOR(S)
Kim, Yong Min; Lee, Soo Young; Koh, Hyoung Jun
PUB. DATE
October 2010
SOURCE
Graefe's Archive of Clinical & Experimental Ophthalmology;Oct2010, Vol. 248 Issue 10, p1387
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: To evaluate the role of preoperative optical coherence tomography (OCT), multifocal electroretinography (mfERG), and fluorescein angiography (FA) as prognostic factors for vision after pars plana vitrectomy (PPV) in diabetic macular edema (DME). Methods: Thirty-five eyes of 34 patients who underwent PPV were retrospectively reviewed. Best-corrected visual acuity (VA) was measured at baseline, and at 3, 6, and 9 months after surgery. Patients were categorized into two groups according to the final VA. Group 1 consisted of eyes with 0.2 or more logMAR lines of visual recovery, the rest of the eyes being placed in group 2. Preoperative FA findings, central macular thickness and mfERG responses at the central macula were evaluated to determine their effect on visual outcome. Results: Eighteen eyes showed improved VA after PPV, and were classified into group 1. Seventeen eyes were placed in group 2. The presence of macular ischemia did not affect the postoperative visual outcome between the groups, although a trend was noted toward macular ischemia with delayed implicit time. P1 implicit time at the central seven hexagons (eccentricity of 0–5°) was the only statistically significant factor predicting unfavorable visual outcome. There was significantly delayed implicit time in group 2 patients compared with those of group 1. MfERG responses at other retinal eccentricities and central macular thickness did not show significant association with visual prognosis. Conclusions: Preoperative mfERG parameters, especially the implicit time, can be useful indicators for predicting functional visual prognosis after PPV in DME.
ACCESSION #
52995812

 

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