Leisure-Time Physical Activity and the Metabolic Syndrome in the Finnish Diabetes Prevention Study

Ilanne-Parikka, Pirjo; Laaksonen, David E.; Eriksson, Johan G.; Lakka, Timo A.; Lindström, Jaana; Peltonen, Markku; Aunola, Sirkka; Keinänen-Kiukaanniemi, Sirkka; Uusitupa, Matti; Tuomilehto, Jaakko
July 2010
Diabetes Care;Jul2010, Vol. 33 Issue 7, p1610
Academic Journal
OBJECTIVE -- To assess the effects of leisure-time physical activity (LTPA) and resistance training on metabolic syndrome (MetS) and its components in a post hoc analysis of the Finnish Diabetes Prevention Study, a randomized controlled lifestyle counseling trial. RESEARCH DESIGN AND METHODS-- A cohort of 486 middle-aged overweight men and women with impaired glucose tolerance were followed for an average of 4.1 years. The intervention and control groups were combined in the analyses. LTPA was assessed by questionnaires, dietary intake by food records, and features of the MetS by anthropometric and biochemical measures annually. Resistance training sessions were documented for 137 participants. RESULTS-- Increased moderate-to-vigorous LTPA, even after adjustments for changes in dietary intakes of total and saturated fat, fiber, and energy, and change in BMI was associated with a greater likelihood for resolution (29.7 vs. 19.1%; P = 0.004 in the upper versus lower third of change) and a lesser likelihood for development (23.5 vs. 44.7%; P = 0.041) of the MetS. Of the components of the MetS, the increase in moderate-to-vigorous LTPA was associated most strongly with improvement of glycemia. Among the 137 participants who participated in resistance training, MetS components were favorable in individuals who were in the upper third of participation rate (median 51 times/year) compared with individuals in the lowest third (median 8.5 times/year). CONCLUSIONS -- Increased moderate-to-vigorous LTPA was associated with a decreased likelihood of developing the MetS and an increased likelihood of its resolution in individuals at high risk for type 2 diabetes.


Related Articles

  • Physical activity and risk of Metabolic Syndrome in an urban Mexican cohort. Méndez-Hernández, Pablo; Flores, Yvonne; Siani, Carole; Lamure, Michel; Dosamantes-Carrasco, L. Darina; Halley-Castillo, Elizabeth; Huitrón, Gerardo; Talavera, Juan O.; Gallegos-Carrillo, Katia; Salmerón, Jorge // BMC Public Health;2009, Vol. 9 Issue 1, p276 

    Background: In the Mexican population metabolic syndrome (MS) is highly prevalent. It is well documented that regular physical activity (PA) prevents coronary diseases, type 2 diabetes and MS. Most studies of PA have focused on moderate-vigorous leisure-time activity, because it involves higher...

  • Effects of Cardiac Autonomic Dysfunction on Mortality Risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Pop-Busui, Rodica; Evans, Gregory W.; Gerstein, Hertzel C.; Fonseca, Vivian; Fleg, Jerome L.; Hoogwerf, Byron J.; Genuth, Saul; Grimm, Richard H.; Corson, Marshall A.; Prineas, Ronald // Diabetes Care;Jul2010, Vol. 33 Issue 7, p1578 

    OBJECTIVE -- Intensive therapy targeting normal blood glucose increased mortality compared with standard treatment in a randomized clinical trial of 10,251 participants with type 2 diabetes at high-risk for cardiovascular disease (CVD) events. We evaluated whether the presence of cardiac...

  • Predicting adult metabolic syndrome from childhood body mass index: follow-up of the New Delhi birth cohort. Sachdev, H. P. S.; Osmond, C.; Fall, C. H. D.; Lakshmy, R.; Ramji, S.; Biswas, S. K. Dey; Prabhakaran, D.; Tandon, N.; Reddy, K. S.; Barker, D. J. P.; Bhargava, S. K. // Archives of Disease in Childhood -- Fetal & Neonatal Edition;Oct2009, Vol. 94 Issue 10, p6 

    Objectives: To assess whether serial measurements of childhood body mass index (BMI) give clinically useful predictions of the risk of developing adult metabolic syndrome and impaired glucose tolerance or type 2 diabetes. Design/setting: Follow-up of a community-based birth cohort in Delhi,...

  • The relative importance of modifiable potential risk factors of type 2 diabetes: a meta-analysis of two cohorts. Laaksonen, Maarit; Knekt, Paul; Rissanen, Harri; Härkänen, Tommi; Virtala, Esa; Marniemi, Jukka; Aromaa, Arpo; Heliövaara, Markku; Reunanen, Antti // European Journal of Epidemiology;Feb2010, Vol. 25 Issue 2, p115 

    Lifestyle factors predict type 2 diabetes occurrence, but their effect in high- and low-risk populations is poorly known. This study determines the prediction of low-risk lifestyle on type 2 diabetes in those with and without metabolic syndrome in a pooled sample of two representative Finnish...

  • Genetic influences on type 2 diabetes and metabolic syndrome related quantitative traits in Mauritius. Jowett, Jeremy B.; Diego, Vincent P.; Kotea, Navaratnam; Kowlessur, Sudhir; Chitson, Pierrot; Dyer, Thomas D.; Zimmet, Paul; Blangero, John // Twin Research & Human Genetics;Feb2009, Vol. 12 Issue 1, p44 

    Epidemiological studies report a high prevalence of type 2 diabetes and metabolic syndrome in the island nation of Mauritius. The Mauritius Family Study was initiated to examine heritable factors that contribute to these high rates of prevalence and consists of 400 individuals in 24 large...

  • The prevalence of metabolic syndrome and its predominant components among pre-and postmenopausal Ghanaian women. Arthur, Fareed Kow Nanse; Frimpong, Michael Adu; Yeboah, James Osei; Mensah, Faustina Obu; Owusu, Lawrence // BMC Research Notes;2013, Vol. 6 Issue 1, p1 

    Background Metabolic Syndrome (MetS) is a clump of risk factors for development of type 2 diabetes mellitus and cardiovascular diseases. Menopause and age are thought to predispose women to the development of metabolic syndrome. This study aimed to estimate the prevalence of MetS and identify...

  • Effectiveness of Dichrostachys glomerata Spice Phenolics in Reduction of Oxidative Stress Associated with Obesity and Type 2 Diabetes; a Randomized, Double-Blind Placebo-Controlled Clinical Trial. Kuate, Dieudonne; Nouemsi Kengne, Anne Pascale; Dakam, William; Omgba Etoundi, Blanche Cunegonde; Djiokeng Paka, Ghislain; Laure Ngondi, Judith; Enyong Oben, Julius // Journal of Food Research;Apr2013, Vol. 2 Issue 2, p1 

    This work evaluated the effect of Dichrostachys glomerata on the improvement of antioxidant biomarkers in obesity and type 2 diabetes participants, in an eight-week randomized, double-blind, placebo-controlled design study. The active (400 mg) or placebo formulation were administered twice daily...

  • 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors as Promising Therapeutic Drugs for Diabetes: Status and Development. Ge, R.; Huang, Y.; Liang, G.; Li, X. // Current Medicinal Chemistry;Feb2010, Vol. 17 Issue 5, Special section p1 

    Glucocorticoids (GC) play a fundamental role in controlling physiologic homeostasis and, when present in excess, can have a detrimental impact on glucose control, blood pressure and lipid levels. The oxidoreductase 11β- hydroxysteroid dehydrogenase type 1 (11β-HSD1) mainly catalyzes the...

  • Balance Training Reduces Falls Risk in Older Individuals With Type 2 Diabetes. Morrison, Steven; Colberg, Sheri R.; Mariano, Mira; Parson, Henri K.; Vinik, Arthur I. // Diabetes Care;Apr2010, Vol. 33 Issue 4, p748 

    OBJECTIVE -- This study assessed the effects of balance/strength training on falls risk and posture in older individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS -- Sixteen individuals with type 2 diabetes and 21 age-matched control subjects (aged 50-75 years) participated. Postural...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics