Zakażenia HCV u dzieci 20 lat po odkryciu wirusa

Pawłowska, Małgorzata
March 2010
Gastroenterologia Polska / Gastroenterology;2010, Vol. 17 Issue 2, p135
Academic Journal
In the first years after the discovery of hepatitis C virus (HCV), the largest HCV-infected group was children who received blood and blood products. In some countries, nosocomial infectious are the source of HCV infection; therefore hospitalized children are a group at risk for this infection. In recent years an increase in vertical HCV infections has been observed. The risk factors of mother-to-child HCV transmission are HIV co-infection, high HCV replication, maternal IVD use, liver dysfunction, and blood loss at delivery. Early HCV RNA examinations in the newborns of HCV-infected mothers are required to diagnose vertical infection. The course of HCV infection in children is usually asymptomatic, with no biochemical liver dysfunction and mild histopathological liver changes. The treatment of chronic HCV infection in children is indicated because of the possible serious clinical consequences as well as the therapy's high efficacy and good tolerance.


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